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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $111.00 |
25 mg | Check Cart for Availability | $356.00 |
About This Item
Empirical Formula (Hill Notation):
C16H12ClN3O
CAS Number:
Molecular Weight:
297.74
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
Clc1cc2ncc(nc2cc1)c3ccc(cc3)NC(=O)C
InChI
1S/C16H12ClN3O/c1-10(21)19-13-5-2-11(3-6-13)16-9-18-15-8-12(17)4-7-14(15)20-16/h2-9H,1H3,(H,19,21)
InChI key
ZQXMPDVGBWOTBY-UHFFFAOYSA-N
Biochem/physiol Actions
CA77.1 is an orally available, brain penetrant, in vivo active and potent enhancer of chaperone-mediated autophagy (CMA). It improves pathology in Alzheimer′s Disease mouse models. CA77.1 activates CMA in vitro without affecting macroautophagy.
orally available, brain penetrant, in vivo active and potent enhancer of chaperone-mediated autophagy (CMA)
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear |
| color white to beige | color white to beige | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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