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SML3208

CPYPP

≥98% (HPLC)

Synonym(s):

4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship TODAYfromMILWAUKEE

$127.00
25 mg

Estimated to ship TODAYfromMILWAUKEE

$514.00

About This Item

Empirical Formula (Hill Notation):
C18H13ClN2O2
CAS Number:
Molecular Weight:
324.76
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$127.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

orange to dark red

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3

InChI

1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)

InChI key

VVZJFICTTKPNCK-UHFFFAOYSA-N

Biochem/physiol Actions

CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.
cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain

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This Item
EMU087531P3750000
description

≥98% (HPLC)

description

targeting mouse Dock2

description

European Pharmacopoeia (EP) Reference Standard

form

powder

form

lyophilized powder

form

-

assay

≥98% (HPLC)

assay

-

assay

-

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

-

color

orange to dark red

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3



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