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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $98.50 |
25 mg | Check Cart for Availability | $396.00 |
About This Item
Empirical Formula (Hill Notation):
C9H18N2O3Pt
CAS Number:
Molecular Weight:
397.33
NACRES:
NA.77
UNSPSC Code:
12352107
Assay:
≥98% (NMR)
Form:
powder
Quality Segment
assay
≥98% (NMR)
form
powder
color
white to beige
solubility
H2O: 2 mg/mL, clear (Warmed)
storage temp.
−20°C
SMILES string
O=C1[O-][Pt+2]2(N[CH2]C3CCC3CN2)[O-]C1C
InChI
1S/C6H12N2.C3H5O3.Pt/c7-3-5-1-2-6(5)4-8;1-2(4)3(5)6;/h5-8H,1-4H2;2H,1H3,(H,5,6);/q-2;-1;+4/p-1/t;2-;/m.0./s1
InChI key
HADHSETVEMCBPU-TYOUJGAFSA-M
Biochem/physiol Actions
Lobaplatin (D-19466) is a third-generation platinum anticancer agent in vitro and in vivo, consisting of ~50:50 mixture of the two trans-1,2-cyclobutanedimethanamine diastereomers in complex with L-lactic acid. Llobaplatin shows antitumor efficacy against various human cancer cancer xenografts and significantly prolongs the survival of mice bearing P388 leukemia (mean life span increase post single i.p. in mg/kg = 46%/4.64 & 77/14.7). Compared to first and second generation platinum compounds, lobaplatin appears to be more stable, less toxic, have a better therapeutic index and may overcome tumor resistance.
Third-generation platinum anticancer agent in vitro and in vivo.
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This Item | |||
|---|---|---|---|
| description ≥98% (NMR) | description powder | description >97% (NMR) | description 99% |
| form powder | form powder | form powder | form solid |
| assay ≥98% (NMR) | assay - | assay >97% (NMR) | assay 99% |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
| solubility H2O: 2 mg/mL, clear (Warmed) | solubility - | solubility DMSO: 0.2 mg/mL (warmed) | solubility - |
| color white to beige | color - | color faint yellow to dark orange | color - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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