This material has not been tested to determine the structure. The sequence is available is the description section of the product page.
SRP3175
TL-1A human
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Synonym(s):
TNFSF15, VEGI
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| Size/SKU | Availability | Price |
|---|---|---|
20 μg | Usually ships in 2 weeks. | $407.00 |
About This Item
NACRES:
NA.32
UNSPSC Code:
12352200
Assay:
≥98% (HPLC), ≥98% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
biological source
human
recombinant
expressed in E. coli
assay
≥98% (HPLC), ≥98% (SDS-PAGE)
form
lyophilized
potency
10.0-100.0 ng/mL
mol wt
22.0 kDa
packaging
pkg of 20 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg endotoxin, tested
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TNFSF15(9966)
General description
TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6. Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues.
Biochem/physiol Actions
TL-1A belongs to the TNF superfamily of ligands. Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues.
Physical form
Lyophilized from 10 mM Tris, pH 8.5 + 75 mM Arginine.
Preparation Note
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Other Notes
QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL
1 of 1
This Item | |||
|---|---|---|---|
| description recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | description Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody | description Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | description Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture |
| technique(s) cell culture | mammalian: suitable | technique(s) immunofluorescence: 0.25-2 μg/mL | technique(s) immunohistochemistry: 1:20- 1:50 | technique(s) cell culture | mammalian: suitable |
| biological source human | biological source rabbit | biological source rabbit | biological source human |
| Gene Information human ... TNFSF15(9966) | Gene Information human ... TNFSF15(9966) | Gene Information human ... TNFSF15(9966) | Gene Information human ... IL15(3600) |
| assay ≥98% (SDS-PAGE), ≥98% (HPLC) | assay - | assay - | assay ≥98% (SDS-PAGE), ≥98% (HPLC) |
| recombinant expressed in E. coli | recombinant - | recombinant - | recombinant expressed in E. coli |
| form lyophilized | form buffered aqueous glycerol solution | form buffered aqueous glycerol solution | form lyophilized |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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Hello, Is this monomer or Trimer version? Also could you give me the sequence? Than you
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