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SRP3203

IFN-lambda 2 from mouse

≥98% (SDS-PAGE & HPLC), recombinant, expressed in E. coli, lyophilized suitable for cell culture

Synonym(s):

IL-28A

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20 μg
Usually ships in 2 weeks.
$397.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
Biological source:
mouse
Recombinant:
expressed in E. coli
Assay:
≥98% (HPLC), ≥98% (SDS-PAGE)
Form:
lyophilized
Mol wt:
19.8 kDa
Impurities:
<0.1 EU/μg endotoxin, tested

$397.00

Usually ships in 2 weeks.
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Product Name

IFN-lambda 2 from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

biological source

mouse

recombinant

expressed in E. coli

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

form

lyophilized

mol wt

19.8 kDa

packaging

pkg of 20 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

color

white to off-white

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... IL28A(338374)

Biochem/physiol Actions

IFN-λ 2 (Ifnl2) belongs to the type III interferon (IFN-λ) family of proteins. It is associated with antiviral, antitumor and immune activities. In a retinal autoimmunity mouse model, Ifnl2 increases the autoimmune disease. Ifnl2 signals via IFN (interferon)-λ receptor complex consisting of IL-10Rβ (interleukin 10 receptor β) and the IL-28Rα chains. The signaling pathway involves JAK1 (Janus kinase 1)/TYK2 (non-receptor tyrosine-protein kinase) tyrosine kinases, transcription factor complex IFN-stimulated gene factor 3 containing STAT1 (signal transducer and activator of transcription 1), STAT2 and IFN regulatory factor (IRF)-9.
Recombinant murine IFN-l2 is a 19.8kDa protein containing 175 amino acid residues.

Physical form

Lyophilized from 20 mM Sodium Phosphate, pH 7.5.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Other Notes

MDPVPRATRL PVEAKDCHIA QFKSLSPKEL QAFKKAKDAI EKRLLEKDMR CSSHLISRAW DLKQLQVQER PKALQAEVAL TLKVWENMTD SALATILGQP LHTLSHIHSQ LQTCTQLQAT AEPKPPSRRL SRWLHRLQEA QSKETPGCLE DSVTSNLFRL LTRDLKCVAS GDQCV

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IFN-lambda 2 from mouse recombinant, expressed in E. coli, &#8805;98% (SDS-PAGE), &#8805;98% (HPLC), suitable for cell culture

Sigma-Aldrich

SRP3203

IFN-lambda 2 from mouse

IFN-lambda 2 human recombinant, expressed in E. coli, &#8805;98% (SDS-PAGE), &#8805;98% (HPLC), suitable for cell culture

Sigma-Aldrich

SRP3060

IFN-lambda 2 human

Human IL-28A / IFN-&#955; ELISA Kit for serum, plasma, cell culture supernatants and urine

Sigma-Aldrich

RAB0291

Human IL-28A / IFN-λ ELISA Kit

description

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

description

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

description

for serum, plasma, cell culture supernatants and urine

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

-

biological source

mouse

biological source

human

biological source

-

assay

≥98% (SDS-PAGE), ≥98% (HPLC)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

assay

-

form

lyophilized

form

lyophilized

form

-

impurities

<0.1 EU/μg endotoxin, tested

impurities

<0.1 EU/μg endotoxin, tested

impurities

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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