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SRP3281

SCD30 LIGAND human

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

Synonym(s):

CD153, CD30L, TNFSF8

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50 μg
Usually ships in 2 weeks.
$437.00

About This Item

NACRES:
NA.77
UNSPSC Code:
12352202
Biological source:
human
Recombinant:
expressed in CHO cells
Assay:
≥95% (HPLC), ≥95% (SDS-PAGE)
Form:
lyophilized
Mol wt:
30.0-50.0 kDa
Impurities:
<0.1 EU/μg endotoxin, tested

$437.00


Usually ships in 2 weeks.

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biological source

human

recombinant

expressed in CHO cells

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

form

lyophilized

potency

10.0-25.0 ng/mL

mol wt

30.0-50.0 kDa

packaging

pkg of 50 μg

impurities

<0.1 EU/μg endotoxin, tested

color

white

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TNFSF8(944)

General description

CD30L binds specifically to CD30 (receptor), which is expressed on activated, but not resting, B and T cells, in lymphomas and various chronically inflamed tissues. CD30L/CD30 interactions initiate a signaling cascade that can ultimately lead to the activation of NF-KappaB. CD30L/CD30 signaling exerts pleiotropic effects on normal cells, including cell death, differentiation, or cell division. Certain diseases, including Hodgkins′s lymphoma, allergic inflammation, diabetes (in NOD mice), and mycobacterial infection can also be affected by CD30L/CD30 signaling. The CD30L gene encodes for a 234 amino acid type II transmembrane protein, which contains a 37 amino acid cytoplasmic sequence, a 25 amino acid transmembrane domain and a 172 amino acid extracellular domain.

Biochem/physiol Actions

CD30 ligand (CD30L) is a type-II membrane-associated glycoprotein protein belonging to the TNF superfamily and is expressed primarily on certain B cells, T cells, and monocytes. Recombinant human soluble CD30L (sCD30L) is a 188 amino acid polypeptide corresponding to the extracellular domain, and contains an 8 residue N-terminal His -Tag.

Physical form

Lyophilized from 1x PBS.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

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RAB1332SRP3306SRP3280
description

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

description

for serum, plasma and cell culture supernatants

description

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

description

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

biological source

human

biological source

-

biological source

human

biological source

human

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

assay

-

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

recombinant

expressed in CHO cells

recombinant

-

recombinant

expressed in E. coli

recombinant

expressed in CHO cells

form

lyophilized

form

-

form

lyophilized

form

lyophilized

UniProt accession no.

P28908

UniProt accession no.

-

UniProt accession no.

P29965

UniProt accession no.

P32970

mol wt

30.0-50.0 kDa

mol wt

-

mol wt

16.3 kDa

mol wt

25.0-35.0 kDa


Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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