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SRP5041

JAK3 (781-end), active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK

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Size/SKUAvailabilityPrice
10 μg
Usually ships in 2 weeks.
$430.00

About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Form:
buffered aqueous glycerol solution
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
Mol wt:
~64 kDa

$430.00

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recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

77-104 nmol/min·mg

mol wt

~64 kDa

NCBI accession no.

NM_000215

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... JAK3(3718)

General description

JAK3 is a member of the JAK family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. Low levels of JAK3 expression is detected in immature hematopoietic cells, which dramatically increases during terminal differentiation of these cells suggesting a role of JAK3 in the differentiation of hematopoietic cells. Mutations in JAK3 are associated with autosomal SCID (severe combined immunodeficiency disease). Mice lacking JAK3 show a severe block in B-cell development at the pre-B stage in bone marrow suggesting that JAK3 is critical for the progression of B-cell development in the bone marrow.

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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JAK3 (781-end), active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

SRP5041

JAK3 (781-end), active, GST tagged human

Jak3 Active human recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE)

Sigma-Aldrich

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Jak3 Active human

Anti-Phospho-Jak3-Y980/981 antibody produced in rabbit

Sigma-Aldrich

SAB5700391

Anti-Phospho-Jak3-Y980/981 antibody produced in rabbit

Jak1 active human recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

Sigma-Aldrich

SRP0335

Jak1 active human

description

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

description

recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE)

description

-

description

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected insect cells

recombinant

-

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥70% (SDS-PAGE)

assay

≥60% (SDS-PAGE)

assay

-

assay

≥70% (SDS-PAGE)

mol wt

~64 kDa

mol wt

65 kDa

mol wt

125, 68, 121

mol wt

34.1 kDa

form

buffered aqueous glycerol solution

form

aqueous solution

form

buffered aqueous solution

form

aqueous solution

specific activity

77-104 nmol/min·mg

specific activity

-

specific activity

-

specific activity

-

Gene Information

human ... JAK3(3718)

Gene Information

human ... JAK3(3718)

Gene Information

human ... JAK3(3718)

Gene Information

human ... JAK1(3716)

Storage Class

10 - Combustible liquids

wgk

WGK 1

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