This product is lyophilized in PBS. Reconstitute in 100uL of endotoxin-free water. Aliquot to avoid multiple freeze/thaw cycles and store at -20°C for up to 3 months.
SRP8010
GPX1 human
recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE)
Promotion Available
Synonym(s):
Cellular glutathione peroxidase, Death receptor 6, GSHPx-1, Glutathione peroxidase 1
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| Size/SKU | Availability | Price |
|---|---|---|
10 μg | Usually ships in 2 weeks. | $410.00 |
About This Item
Form:
lyophilized
Assay:
>90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
~25 kDa by SDS-PAGE
biological source
human
recombinant
expressed in E. coli
tag
His tagged
assay
>90% (SDS-PAGE)
form
lyophilized
mol wt
~25 kDa by SDS-PAGE
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
<1 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GPX1(2876)
General description
GPX1 (glutathione peroxidase 1) is a selenoprotein and the gene is mapped to human chromosome 3p21.3. It is present in the cytoplasm and is widely expressed.
Biochem/physiol Actions
GPX1 (glutathione peroxidase 1) is responsible for scavenging free radicals and derivatives. GPXs reduces lipid hydroperoxides to the corresponding alcohols as well as free hydrogen peroxide to water. Mutations in the GPX1 gene are associated with nonalcoholic fatty liver disease (NAFLD) susceptibility. Mutation in GPX1 at C594T is linked with oxidative stress-associated disorders, including prostate cancer and bladder cancer.
Physical form
Lyophilized from 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl, 1 mM DTT.
Preparation Note
Reconstitute with 100 μL deionized water.
Other Notes
Human GPX1 (aa 1-201) is fused at the C-terminus to a His-tag.
1 of 1
This Item | |||
|---|---|---|---|
| description recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE) | description - | description recombinant, expressed in CHO cells, ≥98% (SDS-PAGE) | description recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE) |
| assay >90% (SDS-PAGE) | assay 95% (SDS-PAGE) | assay ≥98% (SDS-PAGE) | assay >90% (SDS-PAGE) |
| biological source human | biological source human | biological source human | biological source human |
| recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in CHO cells | recombinant expressed in E. coli |
| mol wt ~25 kDa by SDS-PAGE | mol wt 25 kDa | mol wt monomer 46 kDa by calculation | mol wt ~55 kDa by SDS-PAGE |
| form lyophilized | form frozen liquid | form lyophilized | form liquid |
| storage temp. −20°C | storage temp. −70°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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how to aliquots this human Gpx enzyme, and mention the solvent/medium in which GPx enzyme has to be aliquoted for my use?
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