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T0376

Thymine

≥99%, synthetic (organic), powder

Synonym(s):

2,4-Dihydroxy-5-methylpyrimidine, 5-Methyluracil

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Size/SKUAvailabilityPrice
5 g
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$70.00
10 g
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$76.20
25 g
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$87.60
100 g
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$234.00

About This Item

Empirical Formula (Hill Notation):
C5H6N2O2
CAS Number:
65-71-4
Molecular Weight:
126.11
NACRES:
NA.51
PubChem Substance ID:
24899883
UNSPSC Code:
41106305
EC Number:
200-616-1
MDL number:
MFCD00006026
Beilstein/REAXYS Number:
117880
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
1 M NaOH: 50 mg/mL, clear, colorless
Storage temp.:
room temp

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Product Name

Thymine, ≥99%

biological source

synthetic (organic)

Quality Segment

assay

≥99%

form

powder

mp

~320 °C (dec.) (lit.)

solubility

1 M NaOH: 50 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

CC1=CNC(=O)NC1=O

InChI

1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

InChI key

RWQNBRDOKXIBIV-UHFFFAOYSA-N

Gene Information

mouse ... Tymp(72962)

General description

Thymine is one of the four nucleobases, along with adenine, guanine and cytosine found in deoxyribonucleic acids (DNA).

Application

Thymine has been used as a standard nitrogenous base in high-performance liquid chromatography-ultraviolet (HPLC-UV) for the quantification of bone DNA samples, Raman scattering experiments. It has also been used as supplement in C2C12 myoblast cells. Thymine may be used to study chemical processes that affect DNA structure, such a radiation induced radical production leading to base cross-linking reactions and derivitizations. It may be used to study the parameters of hydrogen bonding kinetics and energies with other nucleobases such as adenine.Thymine is used to develop sensitive heavy metal (mercury) detectors based on coordination chemistry and nanoparticle structures.

Biochem/physiol Actions

Thymine used in studying DNA structure byirradtaion methods leading to cross-linking reactions and derivitizations. Thymine dimers are indicative of DNA damage. Thymine is used with metal (mercury) to form thymine−HgII−thymine (T−HgII−T) duplexes. Thymine starvation in bacteria leads to halt in DNA synthesis and is referred as thymine-less death.

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This Item
1724532PHR1345T0895
Thymine ≥99%

Sigma-Aldrich

T0376

Thymine

Zidovudine Related Compound C United States Pharmacopeia (USP) Reference Standard

USP

1724532

Zidovudine Related Compound C

Thymine(Zidovudine Related Compound C) Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1345

Thymine(Zidovudine Related Compound C)

Thymine BioReagent, suitable for cell culture

Sigma-Aldrich

T0895

Thymine

description

≥99%

description

United States Pharmacopeia (USP) Reference Standard

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

BioReagent, suitable for cell culture

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

synthetic

Quality Level

200

Quality Level

-

Quality Level

300

Quality Level

200

form

powder

form

-

form

-

form

powder

assay

≥99%

assay

-

assay

-

assay

≥99% (HPLC)

solubility

1 M NaOH: 50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

1 M NaOH: 50 mg/mL, clear to hazy, colorless to faintly yellow

storage temp.

room temp

storage temp.

-

storage temp.

2-30°C

storage temp.

-

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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