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T103

Trifluperidol hydrochloride

Synonym(s):

4′-Fluoro-4-[4-hydroxy-4-(α,α,α-trifluoro-m tolyl)piperidino]butyrophenone hydrochloride, R 2498, Triperidol

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Size/SKUAvailabilityPrice
25 mg

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$416.00
$353.60

About This Item

Empirical Formula (Hill Notation):
C22H23F4NO2 · HCl
CAS Number:
Molecular Weight:
445.88
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
218-170-1
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated

$353.60

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Quality Segment

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to off-white

solubility

DMSO: ≥20 mg/mL, H2O: soluble, ethanol: moderately soluble

SMILES string

Cl.OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3cccc(c3)C(F)(F)F

InChI

1S/C22H23F4NO2.ClH/c23-19-8-6-16(7-9-19)20(28)5-2-12-27-13-10-21(29,11-14-27)17-3-1-4-18(15-17)22(24,25)26;/h1,3-4,6-9,15,29H,2,5,10-14H2;1H

InChI key

VYGQXRZAHIZHQV-UHFFFAOYSA-N

Gene Information

Application

The interaction of Trifluperidol hydrochloride with NMDA receptors was studied in rat brain buffy coat membranes.

Biochem/physiol Actions

Trifluperidol is a dopamine receptor antagonist with antipsychotic effects used in the treatment of schizophrenia. This neuroleptic penetrates the brain and also affects the glial cells leading to increased release of proinflammatory cytokines. It also alters the metabolism of carbohydrates and amino acids in the brain cortex.

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This Item
SML2841474426193356
description

-

description

≥98% (HPLC)

description

Substrate for fluorogenic assay of α-glucosidase. Has been used in studies of Pompe disease.

description

97%

form

solid

form

powder

form

solid

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥99% (HPLC)

assay

97%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

solubility

DMSO: ≥20 mg/mL, H2O: soluble, ethanol: moderately soluble

solubility

DMSO: 2 mg/mL, clear

solubility

methanol: soluble

solubility

-

storage condition

desiccated

storage condition

-

storage condition

OK to freeze, desiccated, protect from light

storage condition

-

color

white to off-white

color

white to beige

color

white

color

-


Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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