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Thioperamide maleate salt

≥98% (HPLC), histamine H3 receptor antagonist, solid

Synonym(s):

MR-12842, N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide maleate salt

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10 mg

Available to ship TODAYfromMILWAUKEE

$144.00
$122.40
25 mg

Available to ship TODAYfromMILWAUKEE

$345.00
$293.25
100 mg

Available to ship TODAYfromMILWAUKEE

$1,040.00

About This Item

Empirical Formula (Hill Notation):
C15H24N4S · C4H4O4
CAS Number:
Molecular Weight:
408.52
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated, under inert gas

$122.40

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Product Name

Thioperamide maleate salt, solid

assay

≥98% (HPLC)

Quality Segment

form

solid

storage condition

desiccated, under inert gas

color

white

solubility

H2O: >10 mg/mL, DMSO: 12 mg/mL, ethanol: 3 mg/mL

SMILES string

OC(=O)\C=C/C(O)=O.S=C(CC1CCCCC1)N2CCC(CC2)c3c[nH]cn3

InChI

1S/C16H25N3S.C4H4O4/c20-16(10-13-4-2-1-3-5-13)19-8-6-14(7-9-19)15-11-17-12-18-15;5-3(6)1-2-4(7)8/h11-14H,1-10H2,(H,17,18);1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

REZRBLGMJZZSID-BTJKTKAUSA-N

Gene Information

human ... HRH3(11255)

Application

Thioperamide maleate salt was used to study the sympathetic and autonomic nerve activity in mammalian white adipose tissue.

Biochem/physiol Actions

Potent and selective H3 histamine receptor antagonist that crosses the blood-brain barrier.
Thioperamide is a potent and selective H3 histamine receptor antagonist that crosses the blood-brain barrier. It affects the central histaminergic system and decreases the duration of seizures and convulsions in mice. It also improves learning deficit induced by other drugs such as scopolamine.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
C231P1372C6848
description

solid

description

solid, ≥98% (HPLC)

description

≥98% (HPLC), solid

description

≥98% (HPLC), powder

form

solid

form

solid

form

solid

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

storage condition

desiccated, under inert gas

storage condition

desiccated

storage condition

-

storage condition

-

solubility

H2O: >10 mg/mL, ethanol: 3 mg/mL, DMSO: 12 mg/mL

solubility

H2O: >10 mg/mL, DMSO: 100 mg/mL

solubility

DMSO: ~12 mg/mL, H2O: insoluble

solubility

DMSO: 32 mg/mL, H2O: insoluble

color

white

color

white to off-white

color

white to off-white

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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