T1455
TNP-470
≥98% (HPLC)
Synonym(s):
(Chloracetyl) carbamic acid (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester, AGM-1470, NSC 642492, O-Chloracetyl-carbamoyl fumagillol
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $267.00 |
25 mg | Available to ship TODAYfromMILWAUKEE | $1,030.00 |
About This Item
Quality Segment
assay
≥98% (HPLC)
form
solid
solubility
DMSO: >15 mg/mL
originator
Takeda
storage temp.
−20°C
SMILES string
CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@@]3(C)O[C@@H]3C\C=C(\C)C)OC(=O)NC(=O)CCl
InChI
1S/C19H28ClNO6/c1-11(2)5-6-13-18(3,27-13)16-15(24-4)12(7-8-19(16)10-25-19)26-17(23)21-14(22)9-20/h5,12-13,15-16H,6-10H2,1-4H3,(H,21,22,23)/t12-,13-,15-,16-,18+,19+/m1/s1
InChI key
MSHZHSPISPJWHW-PVDLLORBSA-N
General description
Biochem/physiol Actions
Features and Benefits
Preparation Note
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description A cell-permeable Fumagillin analog that inhibits MetAP2, but not MetAP1, methionine aminopeptidase activity, without affecting the inhibitory activity of MetAP2 against HRI- catalyzed eIF-2α phosphorylation. | description ≥95% (HPLC) | description roll, white glass, W × L 1.5 in. (38.1 mm) × 450 ft (137.2 m), pkg of 1 ea |
| assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay - |
| form solid | form solid | form powder | form - |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level - |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. - |
| solubility DMSO: >15 mg/mL | solubility DMSO: 100 mg/mL | solubility DMSO: ≥10 mg/mL | solubility - |
| originator Takeda | originator - | originator Novartis | originator - |
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Storage Class
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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