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T1692

Tianeptine sodium salt hydrate

≥98% (HPLC), opioid receptor agaonist, powder

Synonym(s):

7-[(3-Chloro-6,11-dihydro-6-methyl-dibenzo[c,f][1,2]thiazepine-11-yl)amino]heptanoic acid S,S dioxide sodium salt hydrate

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$371.00
25 mg

Available to ship TODAYfromMILWAUKEE

$1,350.00
$1,147.50

About This Item

Empirical Formula (Hill Notation):
C21H24ClN2NaO4S · xH2O
CAS Number:
Molecular Weight:
458.93 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$371.00


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Product Name

Tianeptine sodium salt hydrate, ≥98% (HPLC), powder

Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to tan

solubility

DMSO: ≥20 mg/mL

originator

Servier

storage temp.

room temp

SMILES string

O.[Na+].CN1c2ccccc2C(NCCCCCCC([O-])=O)c3ccc(Cl)cc3S1(=O)=O

InChI

1S/C21H25ClN2O4S.Na.H2O/c1-24-18-9-6-5-8-16(18)21(23-13-7-3-2-4-10-20(25)26)17-12-11-15(22)14-19(17)29(24,27)28;;/h5-6,8-9,11-12,14,21,23H,2-4,7,10,13H2,1H3,(H,25,26);;1H2/q;+1;/p-1

InChI key

HNTRDGDHBBFLPG-UHFFFAOYSA-M

General description

Tianeptine is a μ-opioid receptor (MOR) as well as a δ-opioid receptor (DOR) agonist.

Application

Tianeptine sodium salt hydrate has been used as a selective serotonin reuptake enhancer (SSRE) positive control during serotonin transporter (SERT) assay in human embryonic kidney 293 cell lines.

Biochem/physiol Actions

Tianeptine is a tricyclic antidepressant that enhances serotonin uptake. This drug can affect neuroprotection, neuronal excitability, memory and anxiety. However, tianeptine is not linked to adverse psychomotor, cognitive, cardiovascular, sleep and bodyweight effects. The drug has a low tendency for abuse and has a positive pharmacokinetic profile.
Tianeptine is least involved in drug interaction as it is not metabolized by cytochrome P450 system in the liver. In hippocampus and amygdala, tianeptine is involved in glutamatergic transmission processes and elicits neuroplasticity.

Features and Benefits

This compound was developed by Servier. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Tianeptine sodium salt hydrate is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml.

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This Item
JN0004PZ0203M7571
description

≥98% (HPLC), powder

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

−20°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

desiccated

solubility

DMSO: ≥20 mg/mL

solubility

H2O: 2 mg/mL, clear

solubility

H2O: 10 mg/mL (clear solution)

solubility

H2O: 15 mg/mL, clear


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

  1. Hello, Please tell me how many pills are in the 5 mg and in the 25 mg container!I would also like to know the purity of the product! Thank you

    1 answer
    1. This product is sold in a powdered format. It is not sold in tablet form. Unless otherwise stated, this product is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.

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