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(+)-α-Tocopherol acetate

Name: (+)-α-Tocopherol acetate
Brand: SIGMA

oil or semi-solid, ~1360 IU/g

Synonym(s):

Vitamin E acetate

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About This Item

Empirical Formula (Hill Notation):

C₃₁H₅₂O₃

CAS Number:

58-95-7

Molecular Weight:

472.74

PubChem Substance ID:

24900095

eCl@ss:

34058007

UNSPSC Code:

12352205

NACRES:

NA.79

EC Number:

200-405-4

MDL number:

MFCD00072052

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Properties

biological source

plant

Quality Segment

200

description

Synthesized from natural α-tocopherol

form

oil or semi-solid

specific activity

~1360 IU/g

color

yellow

mp

~25 °C (lit.)

storage temp.

room temp

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

Description

General description

α-Tocopherol acetate is a fat soluble vitamin and a form of vitamin E. It can be obtained through dietary sources. RRRα-Tocopherol is a natural form of α-tocopherol.

Application

(+)-α-Tocopherol acetate has been used:

as a component of growth medium for retinal cell lines
as an external standard in high performance liquid chromatography (HPLC) to study its composition in leafy vegetables
in the preparation of trans-resveratrol-encapsulated lipid nanocarriers (R-nano)

Biochem/physiol Actions

α-Tocopherol is also known as a radical-chain breaker due to its anti-oxidant property.

Tocopherols (TCP) (vitamin E) are a series (α, β,γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.

Disclaimer

Does not air oxidize.

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This Item	29992	T1157	T3126
Sigma-Aldrich T3001 (+)-α-Tocopherol acetate	Sigma-Aldrich 29992 DL-α-Tocopherol acetate	Sigma-Aldrich T1157 (+)-α-Tocopherol acetate	Sigma-Aldrich T3126 D-α-Tocopherol succinate
description oil or semi-solid, ~1360 IU/g	description tested according to Ph. Eur.	description BioReagent, suitable for insect cell culture, ~1360 IU/g	description semisynthetic, 1210 IU/g
biological source plant	biological source synthetic	biological source plant	biological source semisynthetic
form oil or semi-solid	form liquid	form liquid (or semi-solid)	form powder
storage temp. room temp	storage temp. 2-8°C	storage temp. room temp	storage temp. room temp
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
mp ~25 °C (lit.)	mp -	mp -	mp -
color yellow	color -	color white to yellow	color white to yellow

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Hazard Codes

H413

Precautionary Statements

P273 - P501

Hazard Classifications

Aquatic Chronic 4

Storage Class

10 - Combustible liquids

WGK

WGK 1

PPE (personal protective equipment)

Eyeshields, Gloves

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