T4182
Tyrphostin AG 1478
≥98%, EGFR tyrosine kinase inhibitor, solid
Synonym(s):
N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Estimated to ship TODAYfromMILWAUKEE | $83.90 |
5 mg | Estimated to ship TODAYfromMILWAUKEE | $264.00 $224.40 |
About This Item
Product Name
Tyrphostin AG 1478, ≥98%
Quality Segment
assay
≥98%
form
solid
solubility
0.1 M HCl: soluble <0.4 mg/mL, DMSO:methanol (1:1): soluble 10 mg/mL, clear, colorless, ethanol: soluble 10 mg/mL, methylene chloride: soluble 10 mg/mL, 0.1 M NaOH: insoluble, 2-hydroxypropyl-β-cyclodextrin: insoluble, H2O: insoluble
storage temp.
2-8°C
SMILES string
COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC
InChI
1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
InChI key
GFNNBHLJANVSQV-UHFFFAOYSA-N
Gene Information
human ... EGFR(1956)
mouse ... Egfr(13649)
Application
Biochem/physiol Actions
Features and Benefits
Preparation Note
1 of 1
This Item | |
|---|---|
| description ≥98% | description A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase versus HER2-neu and platelet-derived growth factor receptor kinase. |
| form solid | form solid |
| assay ≥98% | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. −20°C |
| solubility H2O: insoluble, 0.1 M HCl: soluble <0.4 mg/mL, DMSO:methanol (1:1): soluble 10 mg/mL, clear, colorless, 2-hydroxypropyl-β-cyclodextrin: insoluble, 0.1 M NaOH: insoluble, methylene chloride: soluble 10 mg/mL, ethanol: soluble 10 mg/mL | solubility DMSO: 5 mg/mL |
| Gene Information human ... EGFR(1956) | Gene Information - |
Still not finding the right product?
Explore all of our products under Tyrphostin AG 1478
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.