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Trandolapril

Name: Trandolapril
Brand: SIGMA
Price: 166.6 USD
Availability: InStock

≥98% (HPLC), white, powder

Synonym(s):

(2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid, Mavik

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Size/SKU	Availability	Price
10 mg	Available to ship TODAYfromMILWAUKEE	$196.00 $166.60
50 mg	Check Cart for Availability	$777.00

About This Item

Empirical Formula (Hill Notation):

C₂₄H₃₄N₂O₅

CAS Number:

87679-37-6

Molecular Weight:

430.54

NACRES:

NA.77

PubChem Substance ID:

329826801

UNSPSC Code:

12352200

MDL number:

MFCD00865776

Assay:

≥98% (HPLC)

Form:

powder

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Properties

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white

solubility

DMSO: ≥20 mg/mL

originator

Abbott

SMILES string

CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2C3CCCCC3C[C@H]2C(O)=O

InChI

1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1

InChI key

VXFJYXUZANRPDJ-WTNASJBWSA-N

Gene Information

human ... ACE(1636)

Description

Application

Trandolapril has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on responsiveness of human retinal endothelial cells (HRECs) to vascular endothelial growth factor (VEGF).

Biochem/physiol Actions

Studies have reported that trandolapril inhibits atherosclerosis¹ and decreases the occurrence of atrial fibrillation².

Trandolapril is an ACE inhibitor.

Trandolapril is an ACE inhibitor. Trandolapril differs from other ACE inhibitors in that it has a longer biological half-life and a high degree of lipophilicity.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Trandolapril is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml.

Compare Similar Items

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Show Differences

1 of 1

This Item	R0404	P0094	Y0000501
Sigma-Aldrich T4827 Trandolapril	Sigma-Aldrich R0404 Ramipril	Sigma-Aldrich P0094 Perindopril erbumine	Y0000501 Trandolapril
description ≥98% (HPLC), white, powder	description ≥98% (HPLC)	description -	description European Pharmacopoeia (EP) Reference Standard
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay -
form powder	form powder	form powder	form -
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level -
solubility DMSO: ≥20 mg/mL	solubility DMSO: ~18 mg/mL	solubility H₂O: 10 mg/mL, clear	solubility -
color white	color white	color -	color -
originator Abbott	originator Sanofi Aventis	originator Xoma	originator -

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pictograms

GHS08

signalword

Danger

hcodes

H360D

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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