Skip to Content
MilliporeSigma

Skip To

T5694

TRAIL human

recombinant, expressed in NSO cells, >97% (SDS-PAGE), lyophilized powder

Synonym(s):

Apo2 Ligand, Apo2L, TL2, TNF-related apoptosis-inducing ligand

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
10 μg

Available to ship TODAYfromMILWAUKEE

$653.00
$555.05

About This Item

CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
Form:
lyophilized powder
Assay:
>97% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in NSO cells
Mol wt:
24 kDa by SDS-PAGE, predicted mol wt ~21 kDa

$555.05

List Price$653.00Save 15%
Web-Only Promotion

Available to ship TODAYDetails


Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


biological source

human

Quality Segment

recombinant

expressed in NSO cells

description

N-terminal 6X histidine-tagged extracellular domain

assay

>97% (SDS-PAGE)

form

lyophilized powder

mol wt

24 kDa by SDS-PAGE, predicted mol wt ~21 kDa

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... TNFSF10(8743)

Application

TRAIL human was used to induce cytotoxicity in A549, a human lung carcinoma cell line.

Biochem/physiol Actions

TNF-related apoptosis-inducing ligand (TRAIL) is a type II transmembrane protein that belongs to TNF family. It is present in both soluble as well as membrane-bound form and can induce rapid apoptosis of various transformed cell lines but not the normal cells. Additionally, the product can also induces apoptotic cell death in TRAIL-sensitive U343MGcells.
Type II transmembrane protein of the TNF superfamily. Ligand for apoptosis-inducing death receptors DR4 and DR5, decoy receptors DcR1 and DcR2, and osteoprotegerin. Approximately 28% amino acid sequence identity to FAS ligand. Human and mouse TRAIL share 65% sequence identity.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.

Analysis Note

Induces cytotoxicity in mouse L-929 cells in the presence of actinomycin D.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
GF092SRP3237T3573
description

recombinant, expressed in NSO cells, >97% (SDS-PAGE), lyophilized powder

description

Human TRAIL (TNF-Related Apoptosis Inducing Ligand), also called APO2 Ligand, is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells.

description

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

description

>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

biological source

human

biological source

human

biological source

mouse

biological source

human

recombinant

expressed in NSO cells

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in NSO cells

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

assay

>97% (SDS-PAGE)

assay

>98% (SDS-PAGE and HPLC)

assay

≥95% (SDS-PAGE), ≥95% (HPLC)

assay

>90% (SDS-PAGE)

mol wt

24 kDa by SDS-PAGE, predicted mol wt ~21 kDa

mol wt

19.6 kDa

mol wt

20.0 kDa

mol wt

glycolysylated recombinant product ~35 kDa by SDS-PAGE, calculated mol wt 23 kDa

form

lyophilized powder

form

solid

form

lyophilized

form

lyophilized powder


Still not finding the right product?

Explore all of our products under TRAIL human


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters