Key Documents

Anti-τ (Tau) antibody produced in rabbit

Name: Anti-τ (Tau) antibody produced in rabbit
Brand: SIGMA
Price: 510 USD
Availability: InStock

whole antiserum

Synonym(s):

Anti-DDPAC, Anti-FTDP-17, Anti-MAPTL, Anti-MSTD, Anti-MTBT1, Anti-MTBT2, Anti-PPND, Anti-PPP1R103, Anti-TAU, Anti-tau-40

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Size/SKU	Availability	Price
0.2 mL	Available to ship TODAYfromMILWAUKEE	$510.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00164745

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

$510.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

chicken, rat, mouse

technique(s)

western blot: 1:100 using rat or mouse brain tissue extract

UniProt accession no.

P19332

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAPT(4137)

Description

General description

Tau (τ), also known as MAPT (microtubule associated protein tau) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons.

Tau (τ), also known as microtubule associated protein tau (MAPT) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons. Tau is a heat stable microtubule associated protein (MAP) with a molecular weight of 55- 65 kDa.

Immunogen

τ proteins from chicken embryo brain microtubules.

Application

Anti-τ (Tau) antibody produced in rabbit has been used as a primary antibody in western blotting.

Biochem/physiol Actions

Removal of Tau (τ) results in developmental delay and learning disability. It participates in the pathology of Alzheimer′s disease (AD). Tau helps in the assembly and maintenance of microtubule structure.

The antibody shows wide species reactivity. Anti-τ does not react with MAP1, MAP2 or tubulin. the antibody reacts with τ, one of the two major classes of heat stable microtubule-associated proteins (MAPs).

Variation in the MAPT gene encoding tau protein results in frontotemporal dementia. Tau protein acts as a substrate for many kinases.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	T5530	SAB5700526	SAB5700542
Sigma-Aldrich T6402 Anti-τ (Tau) antibody produced in rabbit	Sigma-Aldrich T5530 Monoclonal Anti-τ (Tau) antibody produced in mouse	Sigma-Aldrich SAB5700526 Anti-Phospho-Tau-S519/T522 antibody produced in rabbit	Sigma-Aldrich SAB5700542 Anti-Phospho-Tau-Thr231 antibody produced in rabbit
description whole antiserum	description clone TAU-2, ascites fluid	description -	description -
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
antibody form whole antiserum	antibody form ascites fluid	antibody form affinity isolated antibody	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate -	conjugate -
biological source rabbit	biological source mouse	biological source rabbit	biological source rabbit
shipped in dry ice	shipped in dry ice	shipped in wet ice	shipped in wet ice
Gene Information human ... MAPT(4137)	Gene Information human ... MAPT(4137)	Gene Information human ... MAPT(4137)	Gene Information human ... MAPT(4137)

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Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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Key Documents

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Anti-τ (Tau) antibody produced in rabbit

whole antiserum

Select a Size

About This Item

T6402-.2ML

$510.00

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

contains

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

General description

Immunogen

Application

Biochem/physiol Actions

Disclaimer

Compare Similar Items

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Safety Information

Storage Class

WGK

Flash Point (°F)

Flash Point (°C)

Documentation

Certificates of Analysis (COA)

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