Skip to Content
MilliporeSigma

Skip To

T7165

Tyrphostin 23

≥98%

Synonym(s):

(3,4-Dihydroxybenzylidene)malononitrile, RG-50810

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$144.00
25 mg

Available to ship TODAYfromMILWAUKEE

$577.00

About This Item

Empirical Formula (Hill Notation):
C10H6N2O2
CAS Number:
Molecular Weight:
186.17
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98%
Form:
powder

$144.00


Available to ship TODAYDetails


​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


biological source

synthetic (organic)

Quality Segment

assay

≥98%

form

powder

potency

35 μM IC50

solubility

DMSO: soluble 50 mg/mL, clear, yellow to brownish-yellow

storage temp.

2-8°C

SMILES string

Oc1ccc(cc1O)\C=C(\C#N)C#N

InChI

1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H

InChI key

VTJXFTPMFYAJJU-UHFFFAOYSA-N

Gene Information

human ... CDK2(1017)

Application

Tyrphostin 23 can be used as a tyrosine kinase inhibitor for studying rat ghrelin-induced MAPK stimulation in GH3 cells. Tyrphostin 23 has also been used to analyze its effects on secretoneurin (SN)-induced chemotaxis of neutrophils.

Biochem/physiol Actions

Tyrphostin 23 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
T7040T3434M9440
description

≥98%

description

≥98%

description

solid

description

>98% (HPLC), powder

form

powder

form

solid

form

solid

form

powder

assay

≥98%

assay

≥98%

assay

≥98% (HPLC)

assay

>98% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

DMSO: soluble 50 mg/mL, clear, yellow to brownish-yellow

solubility

DMSO: soluble, chloroform: soluble 50 mg/mL, clear, light yellow

solubility

DMSO: soluble 10 mg/ml, clear, yellow, ethanol: 5 mg/mL, H2O: insoluble

solubility

DMSO: soluble 18 mg/mL, H2O: insoluble

biological source

synthetic (organic)

biological source

-

biological source

synthetic (organic)

biological source

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters