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T7508

Tetracaine hydrochloride

≥99%, Calcium channel blocker

Synonym(s):

4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride

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5 g
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$59.40
25 g
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$108.00
100 g

Estimated to ship onNovember 09, 2026fromMILWAUKEE

$339.00

About This Item

Empirical Formula (Hill Notation):
C15H24N2O2 · HCl
CAS Number:
Molecular Weight:
300.82
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥99%

$59.40


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Product Name

Tetracaine hydrochloride, ≥99%

Quality Segment

assay

≥99%

solubility

chloroform: soluble 30 parts, alcohol: soluble 40 parts, H2O: soluble mg/mL, acetone: insoluble, benzene: insoluble, diethyl ether: insoluble

SMILES string

Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C

InChI

1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H

InChI key

PPWHTZKZQNXVAE-UHFFFAOYSA-N

Application

Topical ophthalmic anesthetic; used for spinal anesthesia
Tetracaine hydrochloride has been used for studying the pharmacological effects of spinal anesthesia. Tetracaine hydrochloride has also been used as a component of protease digestion buffers.

Biochem/physiol Actions

Blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Tetracaine hydrochloride dissolves in water at 50 mg/ml to yield a clear, colorless solution. It is also soluble in 40 parts alcohol and 30 parts chloroform. However, it is practically insoluble in ether benzene or acetone.

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This Item
T0500000PHR1129Y0001002
description

≥99%

description

European Pharmacopoeia (EP) Reference Standard

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

European Pharmacopoeia (EP) Reference Standard

assay

≥99%

assay

-

assay

-

assay

-

Quality Level

200

Quality Level

-

Quality Level

300

Quality Level

-

solubility

alcohol: soluble 40 parts, chloroform: soluble 30 parts, diethyl ether: insoluble, acetone: insoluble, benzene: insoluble, H2O: soluble mg/mL

solubility

-

solubility

-

solubility

-

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)


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Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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