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Anti-TRPC1 antibody produced in rabbit

Name: Anti-TRPC1 antibody produced in rabbit
Brand: SIGMA
Price: 316 USD
Availability: InStock

affinity isolated antibody, lyophilized powder

Synonym(s):

Trpc1 Antibody, Trpc1 Antibody - Anti-TRPC1 antibody produced in rabbit, Anti-Transient receptor potential cation channel, subfamily C, member 1

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Size/SKU	Availability	Price
0.05 mL	Available to ship TODAYfromMILWAUKEE	$316.00
0.2 mL	Available to ship TODAYfromMILWAUKEE	$939.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD02686004

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB CL

Citations:

$316.00

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat

technique(s)

immunohistochemistry: suitable, western blot (chemiluminescent): suitable

UniProt accession no.

Q9QX01

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TRPC1(7220)
mouse ... Trpc1(22063)
rat ... Trpc1(89821)

Description

General description

Transient receptor potential cation channel subfamily C member 1 (TRPC1) is encoded by the gene mapped to human chromosome 3q22-24. The encoded protein is a member of the transient receptor potential (TRP) superfamily of cation channels and is distributed in both glomeruli and glomerular mesangial cells.

Immunogen

Synthetic protein corresponding to amino acids 557-571 of human TRPC1 (GenBank^® Accession No. P48995). The epitope is identical in mouse and rat and highly homologous in bovine and Xenopus.

Biochem/physiol Actions

Transient receptor potential cation channel subfamily C member 1 (TRPC1) facilitates Ca²⁺ entry upon store depletion in a variety of cell types by forming a multimeric complex with other TRPCs. The encoded protein is implicated in the odontoblast-like differentiation of human dental pulp cells (hDPCs). Mutation in the gene is associated with the development type 2 diabetes mellitus (T2D). Decreased expression of the gene leads to hepatocellular carcinoma cell proliferation and thus, TRPC1 can be considered as a potential therapeutic target for hepatocellular carcinoma.

Physical form

Lyophilized at 0.3 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB2105082	HPA021130	HPA038705
Sigma-Aldrich T8276 Anti-TRPC1 antibody produced in rabbit	Sigma-Aldrich SAB2105082 Anti-TRPA1 antibody produced in rabbit	Sigma-Aldrich HPA021130 Anti-TRPC1 antibody produced in rabbit	Sigma-Aldrich HPA038705 Anti-TRPT1 antibody produced in rabbit
description affinity isolated antibody, lyophilized powder	description affinity isolated antibody	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
technique(s) western blot (chemiluminescent): suitable, immunohistochemistry: suitable	technique(s) immunohistochemistry: suitable, western blot: suitable, immunofluorescence: suitable	technique(s) immunohistochemistry: 1:200-1:500, immunofluorescence: 0.25-2 μg/mL	technique(s) immunohistochemistry: 1:200-1:500, immunofluorescence: 0.25-2 μg/mL
Gene Information human ... TRPC1(7220) mouse ... Trpc1(22063) rat ... Trpc1(89821)	Gene Information human ... TRPA1(8989)	Gene Information human ... TRPC1(7220)	Gene Information human ... TRPT1(83707)

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pictograms

GHS06,GHS09

signalword

Danger

hcodes

H301 + H311,H411

pcodes

P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P391 - P501

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Chronic 2

supp_hazards

EUH032

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c