T9011
Trypsinogen, PMSF treated from bovine pancreas
For use as a marker in SDS-PAGE
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| Size/SKU | Availability | Price |
|---|---|---|
1 vial | Available to ship TODAYfromMILWAUKEE | $610.00 |
About This Item
Biological source:
bovine pancreas
$610.00
Available to ship TODAYDetails
biological source
bovine pancreas
Quality Segment
form
powder
mol wt
~24 kDa
packaging
vial of 25 mg
application(s)
detection
storage temp.
2-8°C
Application
Trypsinogen, PMSF treated from bovine pancreas has been used as a non-phosphorylated control to analyze the phospho-protein α-casein from bovine milk by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). It has also been used as a molecular weight marker standard in SDS-PAGE.
Biochem/physiol Actions
Trypsinogen is a pancreatic proteinase and exists as isoenzymes 1 and 2. It is an inactive precursor of trypsin and gets activated by the enteropeptidase found on the brush border membrane of enterocytes in the duodenum. It is also known to proteolytically activate itself. Trypsinogen activation is associated with acute pancreatitis as it causes pancreatic enzyme cascade which activates the remaining zymogens leading to autodigestion of the neighboring tissue. Hereditary pancreatitis was shown to be caused by a Arg-His substitution at residue 117 of trypsinogen causing auto-activation of trypsinogen to trypsin.
1 of 1
This Item | |||
|---|---|---|---|
| description For use as a marker in SDS-PAGE | description Type XI, lyophilized powder, ≥6,000 BAEE units/mg protein | description Type I, ≥5 units/mg solid | description Type V-S, ≥8,500 BAEE units/mg protein (biuret) |
| biological source bovine pancreas | biological source bovine pancreas | biological source bovine pancreas | biological source bovine pancreas |
| application(s) detection | application(s) - | application(s) - | application(s) - |
| form powder | form lyophilized powder | form powder | form powder |
| mol wt ~24 kDa | mol wt 23.8 kDa | mol wt - | mol wt - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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