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UC168

(±)-Bufuralol hydrochloride

≥98% (HPLC), solid, β-Adrenoceptor agonist/antagonist

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Synonym(s):

α-[(tert-Butylamino)methyl]-7-ethyl-2-benzofuranmethanol hydrochloride

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5 mg
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$1,590.00
10 mg
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About This Item

Empirical Formula (Hill Notation):
C16H23NO2·HCl
CAS Number:
Molecular Weight:
297.82
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12161501
EC Number:
262-216-3
MDL number:
Form:
solid

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Product Name

(±)-Bufuralol hydrochloride,

form

solid

Quality Segment

color

white to off-white

mp

143-146 °C

solubility

H2O: soluble, methanol: soluble

storage temp.

2-8°C

SMILES string

Cl.CCc1cccc2cc(oc12)C(O)CNC(C)(C)C

InChI

1S/C16H23NO2.ClH/c1-5-11-7-6-8-12-9-14(19-15(11)12)13(18)10-17-16(2,3)4;/h6-9,13,17-18H,5,10H2,1-4H3;1H

InChI key

KJBONRGCLLBWCJ-UHFFFAOYSA-N

Application

CYP2D6 substrate

Biochem/physiol Actions

β-Blocker. Varying β-adrenoceptor agonist/antagonist activity.
Bufuralol hydrochloride is known to be a non-specific β-receptor inhibitor that has an affinity for β 1 and β 2 receptors. Furthermore, studies have reported that bufuralol hydrochloride can decrease isoproterenol peripheral resistance.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

(±)-Bufuralol hydrochloride is soluble in water and methanol.

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This Item
B016H9414M103
description

-

description

solid

description

≥98% (HPLC), solid

description

solid

form

solid

form

solid

form

solid

form

solid

Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

-

solubility

H2O: soluble, methanol: soluble

solubility

H2O: soluble (Aqueous solutions may be stored for several weeks at -20 °C.), ethanol: soluble, isopropanol: soluble

solubility

DMSO: >10 mg/mL

solubility

H2O: soluble, ethanol: soluble

color

white to off-white

color

white

color

white to off-white

color

white

mp

143-146 °C

mp

-

mp

-

mp

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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