Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

V113

S(+)-γ-Vigabatrin

solid

Synonym(s):

S(+)-γ-Vinyl GABA, S(+)-4-Aminohexenoic acid

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$640.00
$544.00

About This Item

Empirical Formula (Hill Notation):
C6H11NO2
CAS Number:
74046-07-4
Molecular Weight:
129.16
NACRES:
NA.77
PubChem Substance ID:
24900710
UNSPSC Code:
12352200
MDL number:
MFCD00274076
Form:
solid
Quality level:
100

$544.00

List Price$640.00Save 15%
Web-Only Promotion

Available to ship TODAYDetails

​
Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

solid

Quality Level

100

optical activity

[α]/D +11.8°, c = 2.5 in H2O(lit.)

color

off-white

solubility

H2O: >20 mg/mL, ethanol: soluble

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(O)=O)C=C

InChI

1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m1/s1

InChI key

PJDFLNIOAUIZSL-RXMQYKEDSA-N

Application

S(+)-γ-Vigabatrin has been used as a standard in ultra-high-performance-liquid-chromatography (UHPLC).

Biochem/physiol Actions

GABA transaminase inhibitor; anti-convulsant.
γ-Vigabatrin has the potential to treat infantile spasms and seizures. It exhibits therapeutic effects against cocaine and other addictions.

Disclaimer

Hygroscopic

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
V8261UC180S5192
S(+)-γ-Vigabatrin solid

Sigma-Aldrich

V113

S(+)-γ-Vigabatrin

(±)-Vigabatrin

Sigma-Aldrich

V8261

(±)-Vigabatrin

(S)-(+)-Nirvanol

Sigma-Aldrich

UC180

(S)-(+)-Nirvanol

SB 222200 ≥98% (HPLC), solid

Sigma-Aldrich

S5192

SB 222200

form

solid

form

-

form

solid

form

solid

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: >20 mg/mL, ethanol: soluble

solubility

-

solubility

DMF: soluble

solubility

DMSO: soluble ~28 mg/mL, H2O: insoluble

color

off-white

color

-

color

off-white

color

light yellow

optical activity

[α]/D +11.8°, c = 2.5 in H2O(lit.)

optical activity

-

optical activity

-

optical activity

-

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H372

Hazard Classifications

STOT RE 1

target_organs

Eyes,Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
118H4677V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Evaluating risks for vigabatrin treatment
Krauss, Gregory L
Epilepsy currents, 9(5), 125-129 (2009)
Determination of enantiomeric vigabatrin by derivatization with diacetyl-l-tartaric anhydride followed by ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry
Zhao J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1040(5), 199-207 (2017)
M M Robin et al.
European journal of pharmacology, 62(4), 319-327 (1980-04-04)
Unilateral intrastriatal injection of various substances induces a characteristic dyskinetic syndrome in rats. These substances include picrotoxin as well as a series of irreversible GABA-transaminase inhibitors. Using the degree of enzyme inhibition in various brain areas as a measure of
View All Related Papers

Global Trade Item Number

SKUGTIN
V113-5MG04061837429125

Questions

Reviews

No rating value

Active Filters