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V2013

[deamino-Cys1, Val4, D-Arg8]-Vasopressin

≥95%

Sinónimos:

Val4−dDAVP

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Tamaño de envaseSKUDisponibilidadPrecio
1 mg
Comprobar disponibilidad del carrito
MXP 3,075.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C46H65N13O11S2
Peso molecular:
1040.22
NACRES:
NA.32
PubChem Substance ID:
329829030
UNSPSC Code:
51111800
MDL number:
MFCD00080166
Form:
powder
Assay:
≥95%
Biological source:
synthetic (organic)

MXP 3,075.00

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biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥95%

form

powder

solubility

50% acetic acid: soluble 1 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

SMILES string

CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N4CCC[C@H]4C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O

InChI

1S/C46H65N13O11S2/c1-25(2)38-44(69)56-32(22-35(47)61)41(66)57-33(45(70)59-18-7-11-34(59)43(68)54-29(10-6-17-51-46(49)50)39(64)52-23-36(48)62)24-72-71-19-16-37(63)53-30(21-27-12-14-28(60)15-13-27)40(65)55-31(42(67)58-38)20-26-8-4-3-5-9-26/h3-5,8-9,12-15,25,29-34,38,60H,6-7,10-11,16-24H2,1-2H3,(H2,47,61)(H2,48,62)(H,52,64)(H,53,63)(H,54,68)(H,55,65)(H,56,69)(H,57,66)(H,58,67)(H4,49,50,51)/t29-,30+,31+,32+,33+,34+,38+/m1/s1

InChI key

KEBRFHAVFOSSOX-WSFLLCRESA-N

Gene Information

human ... AVPR2(554)
mouse ... AVPR2(12000)
rat ... AVPR2(25108)

Application

[Deamino-Cys1, Val4, D-Arg8]-Vasopressin was used to prepare sample for qualitative detection of desmopressin in plasma by using liquid chromatography-electrospray tandem mass spectrometry.[1]

Biochem/physiol Actions

[Deamino-Pen1, O-Me-Tyr2, Arg8]-Vasopressin is a V1 antagonist that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock.[2]It can also stimulate three acid-base transporters and hence increases the capability of the cell to regulate pHi.[3]

Preparation Note

[deamino-Cys1, Val4, D-Arg8]-Vasopressin dissolves in water at 1 mg/ml to yield a clear, colorless solution.

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1 of 1

Este artículo
V1005V6879T0675
[deamino-Cys1, Val4, D-Arg8]-Vasopressin ≥95%

Sigma-Aldrich

V2013

[deamino-Cys1, Val4, D-Arg8]-Vasopressin

[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate ≥95% (HPLC)

Sigma-Aldrich

V1005

[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate

[Lys8]-Vasopressin ≥98% (HPLC)

Sigma-Aldrich

V6879

[Lys8]-Vasopressin

[D-Ala2]-Deltorphin II ≥97% (HPLC)

Sigma-Aldrich

T0675

[D-Ala2]-Deltorphin II

assay

≥95%

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

form

powder

form

powder

form

powder

form

powder

Gene Information

human ... AVPR2(554)
mouse ... AVPR2(12000)
rat ... AVPR2(25108)

Gene Information

human ... AVPR2(554)
mouse ... AVPR2(12000)
rat ... AVPR2(25108)

Gene Information

human ... AVP(551)

Gene Information

human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)
mouse ... Oprd1(18386), Oprm1(18390)
rat ... Oprd1(24613), Oprm1(25601)

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000486302
0000486302
0000479964
0000479964
0000344858

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Ana Pena et al.
Journal of medicinal chemistry, 50(4), 835-847 (2007-02-16)
The neurohypophyseal peptides arginine vasopressin (AVP) and oxytocin (OT) mediate a wide variety of peripheral and central physiological and behavioral effects by acting on four different G-protein coupled receptors, termed V1a (vascular), V1b (pituitary), V2 (renal), and OT (uterine). We
Simone Esposito et al.
Analytical and bioanalytical chemistry, 402(9), 2789-2796 (2012-02-10)
This work describes a liquid chromatography-electrospray tandem mass spectrometry method for detection of desmopressin in human plasma in the low femtomolar range. Desmopressin is a synthetic analogue of the antidiuretic hormone arginine vasopressin and it might be used by athletes
G Croiset et al.
Brain research, 759(1), 18-23 (1997-06-06)
Subcutaneously (s.c.) administered [Arg8]vasopressin (AVP) potentiated seizures induced by intracerebroventricular (i.c.v.) injection of 1.95 mg pilocarpine (a muscarinic cholinergic agonist). A bell-shaped relation between dose and effect was found. I.c.v. pretreatment with a V1, V2 or oxytocin receptor antagonist was
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SKUGTIN
V2013-1MG04061837480720

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