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V4262

Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse

Name: Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse
Brand: SIGMA
Price: 16206 MXP

clone FLT-11, ascites fluid

Sinónimos:

Anti-Flt1 Receptor, Anti-VEGF R-1

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A ustedes/SKU	Disponibilidad	Precio
0.2 mL	Comprobar disponibilidad del carrito	MXP 16,206.00

Acerca de este artículo

UNSPSC Code:

51111800

NACRES:

NA.41

MDL number:

MFCD01634354

Conjugate:

unconjugated

Clone:

FLT-11, monoclonal

Application:

ELISA (i), ICC, IHC (f), IP, WB

Citations:

MXP 16,206.00

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Propiedades

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

FLT-11, monoclonal

mol wt

antigen 160-200 kDa

contains

15 mM sodium azide

species reactivity

human

technique(s)

immunocytochemistry: suitable, immunohistochemistry (frozen sections): suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1:500 using VEGF Receptor-1 (Flt-1)/Fc Chimera human recombinant

isotype

IgG1

UniProt accession no.

P17948

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... FLT1(2321)

Descripción

General description

Vascular Endothelial Growth Factor Receptor-2 (VEGF R2) is a 160-200kD protein that belongs to protein kinase superfamily and is expressed mainly on the surface of various endothelial cells. It plays a pivotal role in the regulation of angiogenesis, cell migration, cell survival and cancer cell invasion. ASV derived from VEGF receptor type 1 serve as a potential therapeutics for rheumatoid arthritis. Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1antibody can be used in western blotting (diluted 1:500) using VEGF Receptor-1 (Flt-1)/Fc Chimera human recombinant. It can also be used in indirect ELISA. Mouse anti-Vascular Endothelial Growth Factor Receptor-1antibody reacts specifically with an epitope within amino acids 1-251 of the extracellular domain of human VEGF Receptor-1 but not with VEGF Receptor-2 (KDR). The product has shown cross reactivity with the mouse Flt1 receptor.

Vascular endothelial growth factor (VEGF) is also called vasculotropin (VAS) and vascular permeability factor (VPF). It is a homodimeric heparin-binding glycoprotein.

Immunogen

recombinant human VEGF-1 receptor.

Application

Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody can be used in several immunochemical assays like immunohistochemistry, immunocytochemistry and immunoprecipitation for the localization of VEGF-R1.

Biochem/physiol Actions

Mouse monoclonal clone FLT-11 anti-VEGF R-1 antibody reacts specifically with the extracellular domain of human VEGF Receptor-1. The epitope recognized by the antibody resides within amino acid residues 1-251 of the VEGF Receptor-1 molecule. The product does not recognize VEGF Receptor-2 (KDR).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Este artículo	V9134	V3003	E2760
Sigma-Aldrich V4262 Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse	Sigma-Aldrich V9134 Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 antibody produced in mouse	Sigma-Aldrich V3003 Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody produced in mouse	Sigma-Aldrich E2760 Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse
description clone FLT-11, ascites fluid	description clone KDR-1, ascites fluid	description clone 260.4, KDR-2, ascites fluid	description clone 29.1, ascites fluid
biological source mouse	biological source mouse	biological source mouse	biological source mouse
clone FLT-11, monoclonal	clone KDR-1, monoclonal	clone 260.4, KDR-2, monoclonal	clone 29.1, monoclonal
antibody form ascites fluid	antibody form ascites fluid	antibody form ascites fluid	antibody form ascites fluid
Gene Information human ... FLT1(2321)	Gene Information human ... KDR(3791)	Gene Information human ... KDR(3791)	Gene Information human ... EGFR(1956) mouse ... Egfr(13649) rat ... Egfr(24329)
species reactivity human	species reactivity human	species reactivity human	species reactivity pig, human, rat, mouse, canine
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated

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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c