Key Documents

Anti-VMAT2 antibody produced in rabbit

Name: Anti-VMAT2 antibody produced in rabbit
Brand: SIGMA
Price: 4120 SEK

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-SLC18A2, Anti-SVAT, Anti-SVMT, Anti-Solute carrier family 18 (vesicular monoamine), member 2, Anti-VAT2, Anti-VMAT2

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Size/SKU	Availability	Price
100 μg	Please contact Customer Service for Availability	4 120,00 kr

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD02097601

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

4 120,00 kr

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat, human

concentration

~1 mg/mL

technique(s)

immunohistochemistry: 1:100-1:250, western blot: 1:500-1:1,000

UniProt accession no.

Q05940

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SLC18A2(6571)
mouse ... Slc18a2(214084)
rat ... Slc18a2(25549)

Description

General description

Vesicular monoamine transporter 2 (VMAT2) , also known as solute carrier family 18 member A2 (SLC18A2), is a transmembrane protein that acts at nerve terminals. It is expressed in platelets and in central, peripheral and enteric neurons. The gene encoding VMAT2 consists of 16 exons and is mapped to human chromosome 10q25.

Immunogen

synthetic peptide corresponding an internal sequence of human VMAT2. This sequence is identical in mouse and rat.

Application

Anti-VMAT2 antibody produced in rabbit has also been used in immunofluorescence.

Anti-VMAT2 antibody produced in rabbit has been used in western blot analysis.

Biochem/physiol Actions

Vesicular monoamine transporter 2 (VMAT2) modulates the release of neurotransmitters like dopamine, serotonin and γ-amino butyric acid. It has a role in the accumulation of neurotransmitters in synaptic vesicles to prevent toxicity. VMAT2 has been linked to tardive dyskinesia and may be associated with Parkinson′s disease.

Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	WH0006570M1	HPA063797	HPA035180
Sigma-Aldrich V9014 Anti-VMAT2 antibody produced in rabbit	Sigma-Aldrich WH0006570M1 Monoclonal Anti-SLC18A1 antibody produced in mouse	Sigma-Aldrich HPA063797 Anti-SLC18A1 antibody produced in rabbit	Sigma-Aldrich HPA035180 Anti-SLC38A2 antibody produced in rabbit
antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source mouse	biological source rabbit	biological source rabbit
species reactivity mouse, rat, human	species reactivity human	species reactivity human	species reactivity human
clone polyclonal	clone 3A2-E10, monoclonal	clone polyclonal	clone polyclonal

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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