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W4387

Wee1, active from rat

N-terminal GST-tagged, solution

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Size/SKUAvailabilityPrice
60 units
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$975.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
MFCD03459055
Biological source:
rat
Recombinant:
expressed in E. coli

$975.00

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biological source

rat

Quality Segment

recombinant

expressed in E. coli

form

solution

mol wt

~110 kDa

UniProt accession no.

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

rat ... Wee1(308937)

Application

Wee1, active from rat may be used to study apoptotic signaling.

Biochem/physiol Actions

Wee1 is a protein tyrosine kinase that phosphorylates Cdc2 on Tyr15 and hence inactivates the CDK1 and CDK2, which facilitates in the negative regulation of entry of cells into mitosis. Increased level of wee1 stimulates Human Immunodeficiency Virus type 1 (HIV-1) Vpr induced cell cycle arrest at G2/M transition followed by apoptosis.
Protein inhibitor of Cdk2 kinase

Physical form

Solution in 50 mM Tris-HCl, pH 7.5, 1 mM EDTA, 1 mM DTT, 10% Glycerol

Other Notes

One unit of Wee 1 is defined as the amount of Wee 1 which inhibits 90% of the activity of 10 units of Cdk2

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ABE1336HPA068845EMU042191
Wee1, active from rat N-terminal GST-tagged, solution

Sigma-Aldrich

W4387

Wee1, active from rat

Anti-Wee1 from rabbit, purified by affinity chromatography

Sigma-Aldrich

ABE1336

Anti-Wee1

Anti-WEE1 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody

Sigma-Aldrich

HPA068845

Anti-WEE1 antibody produced in rabbit

MISSION® esiRNA targeting mouse Wee1

Sigma-Aldrich

EMU042191

MISSION® esiRNA

description

N-terminal GST-tagged, solution

description

from rabbit, purified by affinity chromatography

description

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody

description

targeting mouse Wee1

biological source

rat

biological source

rabbit

biological source

rabbit

biological source

-

Gene Information

rat ... Wee1(308937)

Gene Information

human ... WEE1(7465)

Gene Information

human ... WEE1(7465)

Gene Information

mouse ... WEE1(22390), Wee1(22390)

application(s)

cell analysis

application(s)

-

application(s)

-

application(s)

-

form

solution

form

-

form

buffered aqueous glycerol solution

form

lyophilized powder

recombinant

expressed in E. coli

recombinant

-

recombinant

-

recombinant

-

UniProt accession no.

Q63802

UniProt accession no.

P30291

UniProt accession no.

P30291

UniProt accession no.

-

Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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