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X2628

Xestospongin C

IP3 receptor Inhibitor, film

Synonym(s):

XeC

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Size/SKUAvailabilityPrice
10 μg

Estimated to ship TODAYfromSAINT LOUIS

$528.00
50 μg

Estimated to ship TODAYfromSAINT LOUIS

$1,920.00

About This Item

Linear Formula:
C28 H50 N2 O2
CAS Number:
Molecular Weight:
446.71
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
eCl@ss:
32160701
Form:
film

$528.00


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Product Name

Xestospongin C, film

form

film

Quality Segment

color

colorless

solubility

DMSO: soluble

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@]12CCCCCC[C@@]3([H])CCCN4CC[C@@]([H])(CCCCCC[C@]5([H])CCCN(CC1)[C@@]5([H])O2)O[C@@]34[H]

InChI

1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24+,25-,26-,27+,28+/m1/s1

InChI key

PQYOPBRFUUEHRC-HCKQMYSWSA-N

General description

Synthetic form of the macrocyclic bis-1-oxaquinolizidine isolated from the Okanowan marine sponge.

Biochem/physiol Actions

Xestospongin C is a potent, reversible and membrane-permeable blocker of IP3-mediated Ca2+ release (IC50=358 nM).
Xestospongin C is a selective, reversible and membrane-permeable inhibitor of IP3 receptor. Reversibly blocks bradykinin- and carbamylcholine- Ca2+ efflux from the endoplasmic reticulum stores.

Features and Benefits

This compound is featured on the InsP3/Ryanodine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Package under nitrogen, tightly sealed.

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This Item
682160MADV638391246CIAH987F035A
description

film

description

An oxaquinolizidine alkaloid isolated from a marine sponge.

description

-

description

-

form

film

form

film

form

-

form

-

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

-

solubility

DMSO: soluble

solubility

ethanol: 1 mg/mL, DMSO: 1 mg/mL, methanol: 1 mg/mL

solubility

-

solubility

-

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

-

color

colorless

color

white to off-white

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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