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Z2126

ZAP-70 Tyrosine Kinase human

≥90% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells (Histidine tagged), buffered aqueous glycerol solution, ≥150 U/mg

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20 μg
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$1,090.00

About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
MFCD03459122
Specific activity:
≥150 U/mg
Assay:
≥90% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected insect cells (Histidine tagged)

$1,090.00

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recombinant

expressed in baculovirus infected insect cells (Histidine tagged)

Quality Segment

assay

≥90% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

≥150 U/mg

mol wt

70 kDa

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... ZAP70(7535)

Application

Human ZAP-70 Tyrosine Kinase was used for mapping the phosphorylation sites on LAT (linker for activation of T cells) for investigating the mechanism of activation of signalling proteins in T cells.

Biochem/physiol Actions

ZAP-70 Tyrosine Kinase is a protein belongs to Syk family and is essential for T cell activation. It facilitates the upregulation of Fas ligand in activation-induced T cell apoptosis. Additionally, it also plays a pivotal role in LFA-1-dependent T Cell Migration.
ZAP-70 is protein tyrosine kinase of the Syk family that is localized exclusively to the cytosol of T cells and natural killer cells. It is required for T cell activation. It is activated by Lck-mediated phosphorylation of its tyrosine residues.

Physical form

Solution in 25 mM HEPES, pH 7.5, containing 150 mM NaCl, 0.5 mM DTT, and 50% glycerol.

Other Notes

One unit will phosphorylate 1 nmol polyglutamic acid:tyrosine per min at 37 °C at pH 7.0.

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SAB4503107RAB1010SAB4700528
ZAP-70 Tyrosine Kinase human ≥90% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells (Histidine tagged), buffered aqueous glycerol solution, ≥150 U/mg

Sigma-Aldrich

Z2126

ZAP-70 Tyrosine Kinase human

Anti-ZAP-70 antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

SAB4503107

Anti-ZAP-70 antibody produced in rabbit

Phosphotyrosine ZAP70 / Tyrosine-protein Kinase ZAP-70 ELISA Kit

Sigma-Aldrich

RAB1010

Phosphotyrosine ZAP70 / Tyrosine-protein Kinase ZAP-70 ELISA Kit

Monoclonal Anti-ZAP70 , (C-terminal) antibody produced in mouse clone ZAP-03, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

SAB4700528

Monoclonal Anti-ZAP70 , (C-terminal) antibody produced in mouse

description

≥90% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells (Histidine tagged), buffered aqueous glycerol solution, ≥150 U/mg

description

affinity isolated antibody

description

-

description

clone ZAP-03, purified immunoglobulin, buffered aqueous solution

specific activity

≥150 U/mg

specific activity

-

specific activity

-

specific activity

-

Gene Information

human ... ZAP70(7535)

Gene Information

human ... ZAP70(7535)

Gene Information

human ... ZAP70(7535)

Gene Information

human ... ZAP70(7535)

assay

≥90% (SDS-PAGE)

assay

-

assay

-

assay

-

form

buffered aqueous glycerol solution

form

buffered aqueous solution

form

-

form

buffered aqueous solution

recombinant

expressed in baculovirus infected insect cells (Histidine tagged)

recombinant

-

recombinant

-

recombinant

-

UniProt accession no.

P43403

UniProt accession no.

P43403

UniProt accession no.

-

UniProt accession no.

P43403

Storage Class

10 - Combustible liquids

WGK

WGK 1

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