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1176007

USP

Dexamethasone

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

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About This Item

Empirical Formula (Hill Notation):
C22H29FO5
CAS Number:
50-02-2
Molecular Weight:
392.46
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749548
MDL number:
MFCD00064136
Beilstein/REAXYS Number:
2066651
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biological source

synthetic

grade

pharmaceutical primary standard

agency

USP

vapor pressure

<0.0000001 kPa ( 25 °C)

API family

dexamethasone

packaging

pkg of 125 mg

manufacturer/tradename

USP

color

white

mp

262-264 °C (lit.)

solubility

acetone: sparingly soluble, chloroform: slightly soluble, ethanol: sparingly soluble, ether: very slightly soluble, methanol: sparingly soluble, water: practically insoluble

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1 of 1

This Item
D0700000BP578PHR1526
Dexamethasone United States Pharmacopeia (USP) Reference Standard

USP

1176007

Dexamethasone

Dexamethasone European Pharmacopoeia (EP) Reference Standard

D0700000

Dexamethasone

Dexamethasone British Pharmacopoeia (BP) Assay Standard

BP578

Dexamethasone

Dexamethasone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1526

Dexamethasone

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

BP

manufacturer/tradename

-

format

neat

format

neat

format

neat

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-30°C

vapor pressure

<0.0000001 kPa ( 25 °C)

vapor pressure

-

vapor pressure

-

vapor pressure

<0.0000001 kPa ( 25 °C)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Ciprofloxacin and Dexamethasone Otic Suspension
  • Dexamethasone
  • Dexamethasone Compounded Oral Suspension
  • Dexamethasone Elixir
  • Dexamethasone Injection
  • Dexamethasone Ophthalmic Suspension
  • Dexamethasone Oral Solution

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

comparable product

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Description
Pricing

related product

Product No.
Description
Pricing

1177000

Dexamethasone phosphate, United States Pharmacopeia (USP) Reference Standard

D0710000

Dexamethasone acetate, European Pharmacopoeia (EP) Reference Standard

D0720000

Dexamethasone sodium phosphate, European Pharmacopoeia (EP) Reference Standard

D0718000

Dexamethasone pivalate, European Pharmacopoeia (EP) Reference Standard

Y0000511

Dexamethasone isonicotinate for impurity C identification, European Pharmacopoeia (EP) Reference Standard

Y0000538

Dexamethasone isonicotinate, European Pharmacopoeia (EP) Reference Standard

Y0001169

Dexamethasone acetate impurity E, European Pharmacopoeia (EP) Reference Standard

Y0001477

Dexamethasone sodium phosphate for peak identification, European Pharmacopoeia (EP) Reference Standard

1176506

Dexamethasone acetate, United States Pharmacopeia (USP) Reference Standard

PHR1527

Dexamethasone Acetate, Pharmaceutical Secondary Standard; Certified Reference Material

1177032

Dexamethasone sodium phosphate, United States Pharmacopeia (USP) Reference Standard

PHR1768

Dexamethasone Sodium Phosphate, Pharmaceutical Secondary Standard; Certified Reference Material

BP108

Dexamethasone sodium phosphate, British Pharmacopoeia (BP) Reference Standard

PHR1628

Dexamethasone Phosphate, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Membrane stabilizing activity?a possible mechanism of action for the anti-inflammatory activity of Cedrus deodara wood oil
Shinde.AU, et al.
Fitoterapia, 70(3), 251-257 (1999)
Dexamethasone Oral Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(6), 1288-1288 (2014)
Dexamethasone Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(6), 1289-1289 (2021)
Dexamethasone
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(4), 1284-1284 (2020)
Dexamethasone Sodium Phosphate Ophthalmic Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(6), 1296-1296 (2016)
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Global Trade Item Number

SKUGTIN
1176007-125MG04061838705204

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