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1228530

USP

Dronedarone hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

N-{2-Butyl-3-[4-(3-dibutylaminopropoxy)benzoyl]benzofuran-5-yl}methanesulfonamide hydrochloride, Multaq, SR-33589B

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Size/SKUAvailabilityPrice
125 mg
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$420.00

About This Item

Empirical Formula (Hill Notation):
C31H44N2O5S · HCl
CAS Number:
141625-93-6
Molecular Weight:
593.22
NACRES:
NA.24
PubChem Substance ID:
329749687
UNSPSC Code:
41116107
MDL number:
MFCD00914940

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grade

pharmaceutical primary standard

agency

USP

API family

dronedarone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c2c(CCCC)oc3ccc(NS(C)(=O)=O)cc23

InChI

1S/C31H44N2O5S.ClH/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3;/h13-18,23,32H,5-12,19-22H2,1-4H3;1H

InChI key

DWKVCQXJYURSIQ-UHFFFAOYSA-N

Gene Information

human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), HCN4(10021), KCNJ2(3759), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

General description

Find answers to frequently asked questions on USP products in USP FAQs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dronedarone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Dronedarone Tablets

Biochem/physiol Actions

Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation.
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibits antiadrenergic properties.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Dronedarone hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1228530

Dronedarone hydrochloride

Dronedarone hydrochloride ≥98% (HPLC)

Sigma-Aldrich

D9696

Dronedarone hydrochloride

USP

USP

1228541

Dronedarone Related Compound A

Amiodarone hydrochloride European Pharmacopoeia (EP) Reference Standard

A0575000

Amiodarone hydrochloride

description

United States Pharmacopeia (USP) Reference Standard

description

≥98% (HPLC)

description

United States Pharmacopeia (USP) Reference Standard

description

European Pharmacopoeia (EP) Reference Standard

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

USP

manufacturer/tradename

EDQM

grade

pharmaceutical primary standard

grade

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

format

neat

format

-

format

neat

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

API family

dronedarone

API family

-

API family

dronedarone

API family

amiodarone

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

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hcodes

H413

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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