Key Documents

Glyburide

Name: Glyburide
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Glybenclamide, 5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide, Glyburide, N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N′-cyclohexylurea

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₂₈ClN₃O₅S

CAS Number:

10238-21-8

Molecular Weight:

494.00

NACRES:

NA.24

PubChem Substance ID:

329749952

UNSPSC Code:

41116107

MDL number:

MFCD00056625

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Properties

grade

pharmaceutical primary standard

agency

USP

API family

glyburide, glibenclamide

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3

InChI

1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)

InChI key

ZNNLBTZKUZBEKO-UHFFFAOYSA-N

Gene Information

human ... ABCC8(6833), KCNJ11(3767)

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glyburide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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This Item	G0325000	BP175	G2539
USP 1295505 Glyburide	G0325000 Glybenclamide	BP175 Glybenclamide	Sigma-Aldrich G2539 Glyburide
description United States Pharmacopeia (USP) Reference Standard	description European Pharmacopoeia (EP) Reference Standard	description British Pharmacopoeia (BP) Reference Standard	description meets USP testing specifications
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade -
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename BP	manufacturer/tradename -
format neat	format neat	format neat	format -
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
Gene Information human ... ABCC8(6833), KCNJ11(3767)	Gene Information human ... ABCC8(6833), KCNJ11(3767)	Gene Information human ... ABCC8(6833), KCNJ11(3767)	Gene Information human ... ABCC8(6833), KCNH2(3757), KCNJ11(3767) rat ... Kcnj1(24521)
agency USP	agency -	agency -	agency USP/NF, meets USP testing specifications

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hcodes

H413

pcodes

P273 - P501

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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