Key Documents

Perindopril erbumine

Name: Perindopril erbumine
Brand: USP
Price: 435 USD
Availability: InStock

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt, Perindopril tert-butylamine, S-9490

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Size/SKU	Availability	Price
100 mg	Check Cart for Availability	$435.00

About This Item

Empirical Formula (Hill Notation):

C₁₉H₃₂N₂O₅· C₄H₁₁N

CAS Number:

107133-36-8

Molecular Weight:

441.60

NACRES:

NA.24

PubChem Substance ID:

329750718

UNSPSC Code:

41116107

MDL number:

MFCD02313824

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Properties

grade

pharmaceutical primary standard

agency

USP

API family

perindopril

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC

InChI

1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1

InChI key

IYNMDWMQHSMDDE-MHXJNQAMSA-N

Gene Information

human ... ACE(1636)

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Perindopril erbumine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Perindopril Erbumine Tablets

Biochem/physiol Actions

Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive.

Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive; becomes hydrolyzed in vivo to the active diacid metabolite; unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II production in vitro. Long-term therapy with this agent has a beneficial effect on the cerebral circulation by improving cerebral perfusion reserve in patients with previous minor stroke.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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This Item	PHR1887	BP1073	Y0000238
USP 1510889 Perindopril erbumine	Supelco PHR1887 Perindopril erbumine	BP1073 Perindopril erbumine	Y0000238 Perindopril tert-butylamine
description United States Pharmacopeia (USP) Reference Standard	description Pharmaceutical Secondary Standard; Certified Reference Material	description British Pharmacopoeia (BP) Reference Standard	description European Pharmacopoeia (EP) Reference Standard
grade pharmaceutical primary standard	grade pharmaceutical secondary standard, certified reference material	grade pharmaceutical primary standard	grade pharmaceutical primary standard
manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename BP	manufacturer/tradename EDQM
format neat	format -	format neat	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
agency USP	agency traceable to Ph. Eur. Y0000238, traceable to USP 1510889	agency -	agency -
Gene Information human ... ACE(1636)	Gene Information human ... ACE(1636)	Gene Information human ... ACE(1636)	Gene Information human ... ACE(1636)

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pictograms

GHS08

signalword

Warning

hcodes

H361d

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c