Certain features of will be down for maintenance Saturday afternoon/evening, February 24th starting at 3:00 pm CT until 9:00 pm CT.

Please note that you still have telephone and email access to our local offices. We apologize for any inconvenience.

Technical Service

Publications: Online library of tutorials, product guides and references

Life Science and Biochemicals
Name Description
Antibody Protocols Detailed immuno procedures, such as Western blotting, ELISA, Immunoprecipitation, etc.
Automated Sequencing SigmaSpin™ Post-Reaction Clean-Up
For removal of unincorporated dyes, excess salts and other interfering components from sequencing reactions.
Biofiles Resource guide for researchers in the Life Sciences, where each installment will highlight products and services tailored to the many individual areas of interest in the Life Sciences.
Biowire Innovative technologies from Sigma® Life Science.
Cold Spring Harbor Laboratory Press RNAi, Genomics and Proteomics protocols
Nucleic Acid Purification Product Guide (DNA & RNA) Product guide for DNA and RNA purification
Enzyme Assay Library Library of enzyme assays with sorting features by enzyme name, EC number etc.
Glycoprotein Analysis Product Guide Product guide including procedures for glycoprotein analysis
Nucleic Acid Amplification Product Guide (PCR) PCR Product Guide will help you will find features and benefits for each product along with appropriate applications data
Proteomic and Protein Expression Product Guide Product guide for Proteomics, Recombinant Protein Expression, and Protein Analysis
Sigma-RBI Handbook
Online Handbook of Receptor Classification and Signal Transduction
Research Poster - Presented by our research scientists at various conferences
Automation Research posters from 2004-present.
Cell Culture Research posters from 2000-present.
Cloning & Expression Research posters from 2004-present.
PCR Research posters from 2004-present.
Proteomics & Protein Expression Research posters from 2004-present.
Interactive Product Catalogs – includes nagivation, search and direct links to products
Cell Culture Manual
Epigenetics Brochure
Nucleic Acid Purification Product Guide (DNA & RNA)
Nucleic Acid Amplification Product Guide (PCR)
Plant Biotechnology Product Guide
Whole Genome Amplification Advisor

Back to top

Analytical / Chromatography
Name Description
Adsorbents for Thermal Desorption Adsorbents for Thermal Adsorption: A review of Carbon Molecular Sieves, Graphitized Carbons, Porous Polymers, and Other adsorbents, utilizing test probes from the EPA Hazardous Pollutant list.
Air Monitoring Products, applications, helpful guides, literature on air sampling methods and adsorbents.
Analytical Standards & Reagents Chemical Standards Explorer: Makes sourcing analytical standards fast and easy.
AnalytiX Analytical newsletter focusing on special analytical applications and products.
Carbohydrate Analysis HPLC Carbohydrate Column Selection Guide: Advantages, limitations, and applications for SUPELCOGEL and SUPELCOSIL columns specifically prepared for various carbohydrate analyses.
Derivatization Reagents Derivatization Reagents: Guide to derivatization for GC analyses.
Discovery Zr Method Development Discovery Zr: Method development guidelines using zirconia HPLC supports.
FAME Analysis FAMEs Analysis: Solvents, Reagents, Columns and Standards for Capillary GC analysis fatty acid methyl esters.
Gas Chromatography Literature Capillary GC, Packed GC, GC Accessories (septa, liners, fittings), and Gas Purification/Management (purifiers, generators).
Liquid Chromatography Troubleshooting your HPLC, from system to column parameters.
Protein and Peptide Separation Discovery BIO HPLC Columns and Capillaries: Solutions to Protein and Peptide Separation Challenges.
Solid Phase Extraction Method Development Guide to SPE methods development.
Solid Phase Extraction Product Selection Discovery SPE: Search for the solid phase extraction product that suits your application needs: multi-well plates, tubes, Büchner funnels, and more.
Solid Phase MicroExtraction SPME theory and optimization for GC and HPLC analyses, with downloadable literature and troubleshooting guide.
Literature & Resources Literature on analytical techniques and sample preparation, for the environmental, food & beverage, petrochemical, and pharmaceutical industries.
The Reporter The Reporter USA: The Reporter provides up-to-date chromaotgraphy applications, products, and techniques, with current offers for customers in the USA.
The Reporter Europe The Reporter Europe: The Reporter presents scientific articles, new applications, background information and current offers for European customers.

Back to top

Materials Science, Chemical Synthesis and Lab Equipment
Name Description
Aldrichimica Acta Articles, written by chemists from around the world, cover a variety of topics usually based on a synthetic theme involving organic, organometallic, bio-organic or inorganic chemistry.
Aldrich Technical Bulletins Technical information bulletins for some of our common used products and equipment.
Asymmetric Synthesis Journal Articles covering topics in asymmetric synthesis.
Biomaterials Tutorial covering the development of biocompatible/biodegradable materials.
Biomolecular NMR Isotopic Labeling in Solid-state NMR of Proteins.
ChemFiles Monthly publication focused on products and research for Chemical Synthesis.
Display and Optoelectronics Tutorial on device basics, light-emitting polymers, charge transport agents, LED materials, etc.
Energy Source Materials Tutorial covering advanced battery and fuel cell research.
Material Matters Quarterly publication addressing research needs in Material Science.
Micro and Nanoelectronics Tutorial covering CVD, ALD, and deposition techniques.
Nanomaterials Tutorial on nanotechnology, nanotools and nanostructured materials.
Polymerization Tools Application and reference guide.
Stable Isotopes Literary review articles on topic related to stable isotopes.
Structural Materials Tutorial covering electronic ceramics and structural materials.

Back to top