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524980

Phthalsäuredibutylester

99%

Dibutyl phthalate

Synonym(e):

n-Butylphthalat, DBP, Dibutylphthalat

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Über diesen Artikel

Lineare Formel:
C6H4-1,2-[CO2(CH2)3CH3]2
CAS-Nummer:
Molekulargewicht:
278.34
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-557-4
Beilstein/REAXYS Number:
1914064
MDL number:
Assay:
99%
Bp:
340 °C (lit.)
Vapor pressure:
1 mmHg ( 147 °C)

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Produktname

Phthalsäuredibutylester, 99%

InChI key

DOIRQSBPFJWKBE-UHFFFAOYSA-N

InChI

1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3

SMILES string

CCCCOC(=O)c1ccccc1C(=O)OCCCC

vapor density

9.6 (vs air)

vapor pressure

1 mmHg ( 147 °C)

assay

99%

form

liquid

autoignition temp.

756 °F

expl. lim.

0.47 %, 236 °F

impurities

≤0.005% Acidity (as Phthalic acid)
≤0.15% water

color

APHA: ≤20

refractive index

n20/D 1.492 (lit.)

pH

7 (20 °C, 10 mg/L)

bp

340 °C (lit.)

mp

−35 °C (lit.)

density

1.043 g/mL at 25 °C (lit.)

functional group

ester

Quality Level

Gene Information

mouse ... Esr1(13982)

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Dieser Artikel
36736D10100001187080
Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

-

assay

99%

assay

≥98%

assay

-

assay

-

form

liquid

form

-

form

-

form

-

impurities

≤0.005% Acidity (as Phthalic acid), ≤0.15% water

impurities

-

impurities

-

impurities

-

vapor density

9.6 (vs air)

vapor density

9.6 (vs air)

vapor density

9.6 (vs air)

vapor density

9.6 (vs air)

refractive index

n20/D 1.492 (lit.)

refractive index

n20/D 1.492 (lit.)

refractive index

n20/D 1.492 (lit.)

refractive index

n20/D 1.492 (lit.)

Application

Weichmacher

General description

Dibutylphthalat (DBP) wird vornehmlich als Weichmacher in verschiedenen Haushaltsprodukten genutzt. Es kann beim Gebrauch oder bei der Entsorgung dieser Produkte in die Umwelt diffundieren oder verdunsten.[1][2] Es wurden daher Studien eingeleitet, um die toxischen und apoptotischen Auswirkungen zu bewerten.[1] Andere Studien haben gezeigt, dass eine Exposition gegenüber hohen Dosen an DBP die Progesteron- und Estradiolproduktion negativ beeinflussen kann.[2]

pictograms

Health hazardEnvironment

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

367.7 °F - open cup

flash_point_c

186.5 °C - open cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Die Dokumentenbibliothek aufrufen

Dibutyl phthalate impairs steroidogenesis and a subset of LH-dependent genes in cultured human mural granulosa cell in vitro.
Adir M
Reproductive Toxicology, 69, 13-18 (2017)
Dibutyl phthalate (DBP)-induced apoptosis and neurotoxicity are mediated via the aryl hydrocarbon receptor (AhR) but not by estrogen receptor alpha (ER?), estrogen receptor beta (ER?), or peroxisome proliferator-activated receptor gamma (PPAR?) in mouse cortical neurons.
Wojtowicz A
Neurotoxicity Research, 31(1), 77-89 (2017)
Damien Hunter et al.
International journal of molecular sciences, 22(8) (2021-05-01)
Xenobiotic exposure during pregnancy and lactation has been linked to perinatal changes in male reproductive outcomes and other endocrine parameters. This pilot study wished to assess whether brief maternal exposure of rats to xenobiotics dibutyl phthalate (DBP) or diethylstilbestrol (DES)
Linda V Sinclair et al.
Immunometabolism, 2(4), e200029-e200029 (2020-09-04)
Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG), a fluorescent analogue of 2-deoxyglucose (2DG), as a substrate
Alin C Dirtu et al.
Environment international, 59, 344-353 (2013-07-31)
Human exposure to chemicals commonly encountered in our environment, like phthalates, is routinely assessed through urinary measurement of their metabolites. A particular attention is given to the specific population groups, such as obese, for which the dietary intake of environmental

Questions

1–4 of 4 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. En que esta disuelto? a que concentración?

    1 answer
    1. This item is in liquid form with a purity of greater than or equal to 99.0%; it is not mixed with anything. Please see the sample Certificate of Anaylsis here: https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/524980-BULKMKCV6253.pdf

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  4. Buenos días, Me gustaría confirmar si el formato "poly bottle" se trata de una botella de plástico y en su caso, si existe algún tipo de diferencia entre los formatos de 25 y 100 mL, puesto que la diferencia de precio es mínima.

    1 answer
    1. Item 524980-25ML is packaged in a HDPE plastic bottle and 524980-100ML is packaged in an amber glass bottle.

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