Accéder au contenu
Merck

G1251

L-Glutamic acid

≥99% (HPLC), suitable for microbiological culture, ReagentPlus®

Synonyme(s) :

(S)-2-Aminopentanedioic acid, Glu

Se connecter pour consulter les tarifs organisationnels et contractuels.

Sélectionner une taille de conditionnement

100 G

41,30 €

500 G

104,00 €

1 KG

153,00 €

5 KG

552,00 €

41,30 €


Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.

Demander une commande groupée

A propos de cet article

Formule linéaire :
HO2CCH2CH2CH(NH2)CO2H
Numéro CAS:
Poids moléculaire :
147.13
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-293-7
MDL number:
Beilstein/REAXYS Number:
1723801

Passer à

Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider

Nom du produit

L-Glutamic acid, ReagentPlus®, ≥99% (HPLC)

InChI key

WHUUTDBJXJRKMK-VKHMYHEASA-N

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

SMILES string

N[C@@H](CCC(O)=O)C(O)=O

agency

suitable for SM 5210

product line

ReagentPlus®

assay

≥99% (HPLC)

form

powder

technique(s)

microbiological culture: suitable

color

white to off-white

mp

205 °C (dec.) (lit.)

solubility

1 M HCl: soluble 100 mg/mL

density

1.54 g/cm3 at 20 °C

cation traces

C: 40.4-41.2%
N: 9.2-9.8%

Quality Level

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Comparer avec des articles similaires

Voir la comparaison complète

Montrer les différences

1 of 4

Cet article
G84154944995436
form

powder

form

powder

form

powder

form

-

assay

≥99% (HPLC)

assay

98.5-100.5%

assay

≥99.5% (NT)

assay

-

technique(s)

microbiological culture: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

product line

ReagentPlus®

product line

-

product line

BioUltra

product line

TraceCERT®

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

solubility

1 M HCl: soluble 100 mg/mL

solubility

1 M HCl: 100 mg/mL

solubility

1 M HCl: 1 M at 20 °C, clear, colorless

solubility

-

Application

L-Glutamic acid has been used to enhance endogenous acetylcholine overflow.[1] It has been used as a supplement in the growth medium of meat-Spoiling Pseudomonas fragi 72. [2]

Biochem/physiol Actions

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
Glutamic acid, or glutamate, the salt form of glutamic acid, functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as γ-aminobutyric acid.[3] Glutamic acid also plays a key role in many metabolic pathways, that controls growth, reproduction, maintenance and immunity.[4] It is converted to α-ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle, and a precursor for the biosynthesis of nucleic acids and certain amino acids.[5][4] In cells, glutamine is converted to glutamate by the enzyme glutaminase.[5]
Glutamine serves as a source of energy for rapidly dividing cells comprising lymphocytes, enterocytes, macrophages and tumors. Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signaling. It is also known to be associated with the inhibition of apoptosis.[4]

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Mixed carbon source utilization of meat-spoiling Pseudomonas fragi 72 in relation to oxygen limitation and carbon dioxide inhibition.
Molin G.
Applied and Environmental Microbiology, 49(6), 1442-1447 (1985)
Glutamic acid, twenty years later.
Garattini S
The Journal of Nutrition, 130, 901S-909S (2000)
Cristina Giaroni et al.
European journal of pharmacology, 476(1-2), 63-69 (2003-09-13)
Several reports suggest that enteric cholinergic neurons are subject to a tonic inhibitory modulation, whereas few studies are available concerning the role of facilitatory pathways. Glutamate, the main excitatory neurotransmitter in the central nervous system (CNS), has recently been described
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
DeBerardinis RJ
Cell Metabolism, 7(1), 11-20 (2008)
Jasdeep Saini et al.
Journal of clinical medicine, 9(10) (2020-10-15)
In many neurodegenerative and muscular disorders, and loss of innervation in sarcopenia, improper reinnervation of muscle and dysfunction of the motor unit (MU) are key pathogenic features. In vivo studies of MUs are constrained due to difficulties isolating and extracting

Articles

Amino Acid Codon Wheel for fast RNA translation. Find which amino acid is translated from your RNA sequence quickly and easily.

Contenu apparenté

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

Product Information Sheet

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. How to solubilize in water?

    1 answer
    1. The solubility in water at 25 °C has been reported to be 8.6 mg/ml. Please see the link below to review the product datasheet:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/262/871/g1251pis.pdf

      Helpful?

Reviews

No rating value

Active Filters

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique