85605

Spermine tetrahydrochloride

BioUltra, for molecular biology, ≥99.5% (AT)

• Synonym(s): N,N′-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
• Empirical Formula (Hill Notation): C₁₀H₂₆N₄ · 4HCl
• CAS Number: 306-67-2
• Molecular Weight: 348.18
• Beilstein: 3911771
• Número EC: 206-189-8
• Número MDL: MFCD00012914
• ID de substância PubChem: 57653056
• NACRES: NA.26

Properties

• grau: for molecular biology
• Nível de qualidade: 300
• linha de produto: BioUltra
• teor: ≥99.5% (AT)
• forma: powder
• Impurezas: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• pH: 4.5-7.0 (25 °C, 1 M in H₂O)
• pf: 310-311 °C (dec.) (lit.)
• solubilidade: H₂O: 1 m at 20 °C, clear, colorless to almost colorless
• traços de ânion: sulfate (SO₄^2-): ≤50 mg/kg
• traços de cátion: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Absorção UV: λ: 260 nm A_max: 0.2; λ: 280 nm A_max: 0.15
• SMILES string: Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
• InChI: 1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
• InChI key: XLDKUDAXZWHPFH-UHFFFAOYSA-N

Description

Embalagem

1, 5, 25 g

Aplicação

Used to precipitate DNA from low salt aqueous buffers.

Ações bioquímicas/fisiológicas

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Outras notas

Spermine precipitation of DNA

Safety Information

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315 - H319
• Declarações de precaução: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2
• Código de classe de armazenamento: 13 - Non Combustible Solids
• WGK: WGK 3
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves