P186
PD 123,319 di(trifluoroacetate) salt hydrate
powder, ≥98% (HPLC)
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Ensaio
≥98% (HPLC)
forma
powder
condição de armazenamento
desiccated
solubilidade
H2O: 10 mg/mL, clear
temperatura de armazenamento
2-8°C
SMILES string
O.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c4ccccc4)c5ccccc5)cc1C
InChI
1S/C31H32N4O3.2C2HF3O2.H2O/c1-21-16-22(14-15-26(21)33(2)3)18-34-20-32-25-19-35(28(31(37)38)17-27(25)34)30(36)29(23-10-6-4-7-11-23)24-12-8-5-9-13-24;2*3-2(4,5)1(6)7;/h4-16,20,28-29H,17-19H2,1-3H3,(H,37,38);2*(H,6,7);1H2/t28-;;;/m0.../s1
InChI key
PTSUEYBWHKDYBS-FPCIESGBSA-N
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This Item | S6883 | G3416 | T2269 |
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form solid | form powder |
| storage condition desiccated | storage condition (Keep container tightly closed in a dry and well-ventilated place.) | storage condition - | storage condition - |
| solubility H2O: 10 mg/mL, clear | solubility 0.1 M acetic acid: 1 mg/mL | solubility H2O: 30 mg/mL | solubility - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
Aplicação
- To determine the effect of Angiotensin II (Ang II) on alveolar fluid clearance (AFC).
- To study the effect of PD123319 on AngII-induced abdominal aortic aneurysms (AAAs).
- To study its effect on Ang II-induced LRP1 overexpression and function in vascular smooth muscle cells (VSMCs) culture.
Ações bioquímicas/fisiológicas
Atenção
Informações legais
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
WGK
WGK 3
Ponto de fulgor (ºF)
Not applicable
Ponto de fulgor (ºC)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Gloves
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