F124

Furafylline

≥98% (HPLC), powder, caffeine inhibitor

• Synonym(e): 3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione
• Empirische Formel (Hill-System): C₁₂H₁₂N₄O₃
• CAS-Nummer: 80288-49-9
• Molekulargewicht: 260.25
• UNSPSC Code: 41106305
• PubChem Substance ID: 24278813
• NACRES: NA.77
• MDL number: MFCD00153799
• eCl@ss: 32119108
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Furafylline, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• mp: 274-275 °C
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: room temp
• SMILES string: CN1C(=O)N(Cc2ccco2)c3nc(C)[nH]c3C1=O
• InChI: 1S/C12H12N4O3/c1-7-13-9-10(14-7)16(6-8-4-3-5-19-8)12(18)15(2)11(9)17/h3-5H,6H2,1-2H3,(H,13,14)
• InChI key: KGQZGCIVHYLPBH-UHFFFAOYSA-N
• Gene Information: human ... CYP1A2(1544)

Beschreibung

Biochem/physiol Actions

Furafylline is a methyl xanthine derivative with longer duration of action than theophylline and an inhibitor of cytochrome P4501A2.

Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.

Features and Benefits

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)