SML0804

(S)-CPP sodium salt

≥96% (HPLC)

• Synonym(e): (S)-2-Chloro-3-phenylpropanoic acid sodium salt, (aS)-a-chloro-benzenepropanoic acid sodium salt
• Empirische Formel (Hill-System): C₉H₈ClO₂ · Na
• CAS-Nummer: 194979-70-9
• Molekulargewicht: 206.60
• NACRES: NA.77
• PubChem Substance ID: 329825602
• UNSPSC Code: 12352200
• MDL number: MFCD28118980
• Assay: ≥96% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥96% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [O-]C([C@@H](Cl)CC1=CC=CC=C1)=O.[Na+]
• InChI: 1S/C9H9ClO2.Na/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,11,12);/q;+1/p-1/t8-;/m0./s1
• InChI key: HMHPCHNNVOLTFC-QRPNPIFTSA-M

Beschreibung

Biochem/physiol Actions

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase.

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC₅₀ = 6.3 μM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable