If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
S6501
Streptomicina
powder
Sinonimo/i:
2-[(1S,2R,3R,4S,5R,6R)-5-(diaminomethylideneamino)-2-[(2R,3S,4S,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-methylamino-oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyl-oxolan-2-yl]oxy-3,4,6-trihydroxy-cyclohexyl]guanidine
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CHF 35.00
CHF 79.80
CHF 143.00
CHF 234.00
CHF 1’440.00
Informazioni su questo articolo
Vai a
Origine biologica
Streptomyces griseus
Livello qualitativo
Stato
powder
Potenza
≥720 I.U. per mg
PM
calculated mol wt 1457.38
Condizioni di stoccaggio
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
Colore
white to off-white
Spettro attività antibiotica
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
Modalità d’azione
protein synthesis | interferes
Temperatura di conservazione
2-8°C
Stringa SMILE
OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@@H](O[C@@H](C)[C@]2(O)C=O)O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]3NC(N)=N.CN[C@H]4[C@H](O)[C@@H](O)[C@H](CO)O[C@H]4O[C@H]5[C@@H](O[C@@H](C)[C@]5(O)C=O)O[C@@H]6[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]6NC(N)=N
InChI
1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,21+;;;/m00.../s1
QTENRWWVYAAPBI-YZTFXSNBSA-N
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Categorie correlate
1 of 4
Questo articolo | S9137 | S1277 | 85886 |
|---|---|---|---|
| antibiotic activity spectrum Gram-negative bacteria, mycobacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| form powder | form powder | form powder | form liquid |
| biological source Streptomyces griseus | biological source - | biological source - | biological source - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| potency ≥720 I.U. per mg | potency ≥720 I.U. per mg (dried basis) | potency ≥720 I.U. per mg | potency - |
Descrizione generale
Applicazioni
Azioni biochim/fisiol
Modalità di resistenza: Una mutazione in rpsL, un gene per la proteina ribosomiale S12, impedisce il legame della streptomicina con il ribosoma. Inoltre, un′aminoglicoside fosfotransferasi inattiva la streptomicina.
Spettro antimicrobico: La streptomicina è attiva nei confronti dei batteri gram positivi e gram negativi.
Nota sulla preparazione
Altre note
Esclusione di responsabilità
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Oral - Repr. 2
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Articoli
Antibiotics targeting bacterial ribosomes disrupt protein synthesis, a key process in bacterial growth inhibition.
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
Helpful?
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How can the potency of Streptomycin sulfate salt powder S6501 be converted from IU/mg to µg/mg?
1 answer-
The International Unit (IU) of Streptomycin is defined as the activity present in 0.001282 mg or 1.282 µg of the International Standard, as referenced in the literature article below.
According to the reported value from the article above, which is not verified in-house, the following formula is applicable:
Potency (IU/mg dry basis) × 1.282 µg/1 IU = Potency (µg/mg)
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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