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C1909

Sigma-Aldrich

Acide citrique monohydrate

ACS reagent, ≥99.0%

Synonyme(s) :

2-hydroxy-1,2,3-propanetricarboxylic acid monohydrate

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25 G
36,60 €
500 G
57,70 €
1 KG
89,40 €
2.5 KG
211,00 €
12 KG
599,00 €

36,60 €


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Sélectionner une taille de conditionnement

Changer de vue
25 G
36,60 €
500 G
57,70 €
1 KG
89,40 €
2.5 KG
211,00 €
12 KG
599,00 €

About This Item

Formule linéaire :
HOC(COOH)(CH2COOH)2 · H2O
Numéro CAS:
Poids moléculaire :
210.14
Beilstein:
4018641
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.21

36,60 €


En stockDétails


Devis pour commande en gros

Qualité

ACS reagent

Niveau de qualité

Essai

≥99.0%

Forme

powder

Impuretés

Substances carbonizable by hot sulfuric acid, passes test
≤0.005% Insoluble matter

Résidus de calcination

≤0.02%

pKa  

(1) 3.13, (2) 4.76, (3) 6.4

Solubilité

H2O: soluble 54 % (w/w) at 10 °C (Citric acid in water)
H2O: 59.2 % (w/w) at 20 °C (Citric acid in water)
H2O: 84.0 % (w/w) at 100 °C (Citric acid in water)

Traces d'anions

chloride (Cl-): ≤0.001%
oxalate (C2O42-): passes test (limit about 0.05%)
phosphate (PO43-): ≤0.001%
sulfate (SO42-): ≤0.002%

Traces de cations

Fe: ≤3 ppm
Pb: ≤2 ppm

Groupe fonctionnel

carboxylic acid

Chaîne SMILES 

OC(CC(O)(C(O)=O)CC(O)=O)=O.O

InChI

1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2

Clé InChI

YASYEJJMZJALEJ-UHFFFAOYSA-N

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Description générale

Citric acid monohydrate is an organic acid. Its molar enthalpy of solution in water has been reported to be ΔsolHm (298.15K, m = 0.0203molkg-1) = (29061±123)Jmol-1.[1] It can be produced by crystallization from mother liquor of citric acid solution at 20-25°C during citric acid synthesis.[2] An investigation of its crystal growth kinetics indicates that growth is linearly dependent on size.[3]

Citric acid monohydrate is an organic weak acid used as a natural preservative in food and beverage products.[4]

Application

Citric acid monohydrate was used in the preparation of citric acid solution employed in the acetone method of 68Ga pre-purification and radiolabeling technique.[5]
It may be used:
  • As release-modifying agent to improve the release of diltiazem hydrochloride from melt extruded Eudragit RS PO tablets.[6]
  • To prepare citrate buffer for use in the preparation of platelets for intravital microscopy.[7]
  • To prepare Tris-citrate buffer employed for the electrophoresis of bacterial enzymes.[8]

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

345.0 °F - closed cup

Point d'éclair (°C)

173.9 °C - closed cup

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Eco-friendly rice husk pre-treatment for preparing biogenic silica: Gluconic acid and citric acid comparative study
Setiawan WK and Chiang KY
Chemosphere, 179, 130541-130541 (2021)
Size dependency of citric acid monohydrate growth kinetics.
Bravi M and Mazzarotta B.
Chemical Engineering Journal, 70(3), 203-207 (1998)
Michael K Schultz et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 76, 46-54 (2012-10-03)
A new NaCl based method for preparation of gallium-68 labeled radiopharmaceuticals has been adapted for use with an automated gallium-68 generator system. The method was evaluated based on 56 preparations of [(68)Ga]DOTATOC and compared to a similar acetone-based approach. Advantages
Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics.
R K Selander et al.
Applied and environmental microbiology, 51(5), 873-884 (1986-05-01)
Sandra U Schilling et al.
International journal of pharmaceutics, 361(1-2), 158-168 (2008-06-28)
Incomplete drug release and particle size-dependent dissolution performance can compromise the quality of controlled release matrix systems. The objective of the current study was to investigate the ability of citric acid monohydrate (CA MH) to enhance the release of diltiazem

Articles

LC-MS/MS-based determination of 19 sulfonamides, 13 quinolones, and 3 tetracycline drug residues in pork meat samples using Supel™ Swift HLB for extraction.

Questions

1–3 sur 3 questions  
  1. I need to prepare 100 ml of 1 molar citric acid solution. How do I prepare this and which product do I need to buy?

    1 réponse
    1. The volume of 100 mL is equivalent to 0.1 Liters. And 1 molar (1 mole per liter) times 0.1 liters equals 0.1 moles. The molecular weight for Citric Acid Monohydrate is 210.14 grams per mole. And 0.1 moles times 210.14 grams per mole equals 21.0 grams. So to prepare the solution, dissolve 21.0 grams of citric acid monohydrate in about 75 mL of pure water, then bring the final volume to 100 mL. Citric Acid Monohydrate is very soluble in water.
      As far as which product to buy, many grades of citric acid and citric acid monohydrate are listed. Please contact your local Technical Service group and describe your intended application so that they can help you choose the appropriate grade.

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 réponse
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 réponse
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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