Principaux documents

Voir toute la documentation

Passer à

166312K

Collagen Mimetic peptides MAPTRIX-C-TAIPSCPEGTVPLYS

Name: Collagen Mimetic peptides MAPTRIX-C-TAIPSCPEGTVPLYS
Brand: SIGMA

animal-free ECM peptides, solution, 0.5 mg/mL protein, suitable for cell culture

Synonyme(s) :

MAPTrix^™ Technology

Se connecter pour consulter les tarifs organisationnels et contractuels.

A propos de cet article

UNSPSC Code:

12352202

NACRES:

NA.75

Form:

aqueous solution

Technique(s):

cell culture | mammalian: suitable

Concentration:

0.5 mg/mL protein

Mol wt:

~24.1 kDa

La commercialisation de ce produit a été interrompue. Contacter notre Service techniquepour obtenir une assistance

Propriétés

Nom du produit

MAPTRIX-C-TAIPSCPEGTVPLYS, Collagen Mimetic, aqueous solution

sterility

Filtered sterilized solution

form

aqueous solution

mol wt

~24.1 kDa

packaging

pkg of 2.5 mg

concentration

0.5 mg/mL protein

technique(s)

cell culture | mammalian: suitable

binding specificity

Domain: α3(IV) NC1
Binding Motif: TAIPSCPEGTVPLYS

shipped in

ambient

storage temp.

2-8°C

Description

Application

MAPTrix^™ Technology provides a true extracellular microenvironment (ECM) by presenting combinatorial peptide motifs. The ECM, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions.Currently existing technology offers simple and merely adequate environments that facilitate simple cell processes such as cellular adhesion.[1][2] The simple presentation of cell adhesion motifs is not optimal for controlling more integrated processes. Crosstalk among signaling pathways act synergistically to enhance cellular responses such as cell adhesion or proliferation.[3] A study showed that a combination of extracellular matrix derived peptides presented on a surface may enhance cell adhesion strength and focal adhesion assembly. The combinatorial presentation of ECM peptides on cell growth surfaces may also promote elevated proliferation rates of primary or stem cells.[4][5][6]

Features and Benefits

Biochemically-defined, animal-free cell culture surfaces designed to enhance cell performance
MAPTrix^™ produces a uniform ECM surface that provides a highly controlled 2D extracellular microenvironment for cell cultures and related applications
Adhesion properties of the mussel adhesive protein makes the coating reproducible & reliable

Legal Information

MAPTrix is a trademark of Kollodis Biosciences

Comparer avec des articles similaires

Voir la comparaison complète

Montrer les différences

1 of 1

Cet article	166314K	162292K	164422K
Sigma-Aldrich 166312K MAPTRIX-C-TAIPSCPEGTVPLYS	Sigma-Aldrich 166314K MAPTRIX-C-TAIPSCPEGTVPLYS	Sigma-Aldrich 162292K MAPTRIX-L-TWYKIAFQRNRK	Sigma-Aldrich 164422K MAPTRIX-L-KAFDITYVRLKF
sterility Filtered sterilized solution	sterility Filtered sterilized solution	sterility Filtered sterilized solution	sterility Filtered sterilized solution
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
concentration 0.5 mg/mL protein	concentration 1.0 mg/mL protein	concentration 0.5 mg/mL protein	concentration 0.5 mg/mL protein
form aqueous solution	form aqueous solution	form aqueous solution	form aqueous solution
mol wt ~24.1 kDa	mol wt ~24.1 kDa	mol wt ~24.2 kDa	mol wt ~24.1 kDa
binding specificity Domain: α3(IV) NC1 Binding Motif: TAIPSCPEGTVPLYS	binding specificity Domain: α3(IV) NC1 Binding Motif: TAIPSCPEGTVPLYS	binding specificity Receptor: α6β1 Domain: α1 LG2 - AG32 Binding Motif: TWYKIAFQRNRK	binding specificity Receptor: αvβ3, α5β1 Domain: γ1 chain - C16 Binding Motif: KAFDITYVRLKF

Still not finding the right product?

Explore all of our products under

flash_point_f

Not applicable

flash_point_c

Not applicable

Classe de stockage

12 - Non Combustible Liquids

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

Si vous avez besoin d'assistance, veuillez contacter Service Clients

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Signalling by adhesion receptors.

S J Fashena et al.

Nature cell biology, 2(12), E225-E229 (2001-01-09)

Over the past twenty years, intensive research has enabled us to identify components of specific signalling pathways downstream of an array of adhesion and growth-factor receptors. The first Gordon Research Conference on 'Signalling by Adhesion Receptors', which took place in

Mixed extracellular matrix ligands synergistically modulate integrin adhesion and signaling.

Catherine D Reyes et al.

Journal of cellular physiology, 217(2), 450-458 (2008-07-10)

Cell adhesion to extracellular matrix (ECM) components through cell-surface integrin receptors is essential to the formation, maintenance and repair of numerous tissues, and therefore represents a central theme in the design of bioactive materials that successfully interface with the body.

Characterization of integrin engagement during defined human embryonic stem cell culture.

Ying Meng et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(4), 1056-1065 (2009-11-26)

Human embryonic stem (hES) cells are pluripotent, capable of differentiating into any cell type of the body, and therefore have the ability to provide insights into mechanisms of human development and disease, as well as to provide a potentially unlimited

Afficher tous les articles scientifiques apparentés

Numéro d'article de commerce international

Référence	GTIN
166312K-2.5MG	04061838748898

Questions

Évaluations

Aucune valeur de notation