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F0806

Factor IX human

Name: Factor IX human
Brand: SIGMA

aqueous glycerol solution, ≥145 units/mg protein

Synonyme(s) :

Christmas factor, Plasma thromboplastin component

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A propos de cet article

Numéro CAS:

9001-28-9

UNSPSC Code:

12352202

NACRES:

NA.61

MDL number:

MFCD00163303

Form:

aqueous glycerol solution

Biological source:

human

Mol wt:

55 kDa

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Propriétés

biological source

human

Quality Segment

200

form

aqueous glycerol solution

specific activity

≥145 units/mg protein

mol wt

55 kDa

technique(s)

ligand binding assay: suitable

UniProt accession no.

P00740

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... F9(2158)

Description

General description

Factor IX is a 55 kDa single chain vitamin K-dependent plasma zymogen which plays a key role in the intrinsic and extrinsic blood coagulation systems.

Application

Factor IX is plasma zymogen key to blood coagulation systems. It has been used in studies of portal vein thrombosis (PVT) in hepatocellular carcinoma (HCC). It has been found that abnormalities in factor IX contribute to PVT in HCC patients. Additionally, it has been used in studies of changes in the coagulation system in patients with inflammatory bowel disease (IBD).

Physical form

Aqueous solution containing 50% (v/v) glycerol

Other Notes

One unit is equivalent to the Factor IX activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.

View this factors role in the Coagulation Cascade

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Cet article	F1020	F0652	F2645
Sigma-Aldrich F0806 Factor IX human	Sigma-Aldrich F1020 Anti-Factor IX antibody, Mouse monoclonal	$Anti-Factor IX antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich F0652 Anti-Factor IX antibody produced in rabbit	Sigma-Aldrich F2645 Anti-Factor IX antibody, Mouse monoclonal
description aqueous glycerol solution, ≥145 units/mg protein	description clone HIX-5, purified from hybridoma cell culture	description IgG fraction of antiserum, buffered aqueous solution	description clone HIX-1, purified from hybridma cell culture
technique(s) ligand binding assay: suitable	technique(s) indirect ELISA: suitable, western blot: 1:500	technique(s) indirect ELISA: 1:5,000, western blot: 1:3,000 using using reduced and non-reduced human plasma blots	technique(s) indirect ELISA: suitable, western blot: 2-4 μg/mL
biological source human	biological source mouse	biological source rabbit	biological source mouse
mol wt 55 kDa	mol wt -	mol wt -	mol wt -
form aqueous glycerol solution	form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution
specific activity ≥145 units/mg protein	specific activity -	specific activity -	specific activity -
shipped in wet ice	shipped in dry ice	shipped in dry ice	shipped in dry ice

Classe de stockage

10 - Combustible liquids

Que se passe-t-il ?

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

EPI (équipement de protection individuelle)

Eyeshields, Gloves, type N95 (US)

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