PLA0010

Sigma-Aldrich

Goat anti-RENT1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonyme(s):
pNORF1, RENT1, smg-2 homolog, KIAA0221, nonsense mediated mRNA decay factor (C. elegans), UP Frameshift 1, smg-2, ATP-dependent helicase RENT1, up-frameshift suppressor 1 homolog, NORF1, UPF1 regulator of nonsense transcripts homolog, delta helicase, HUPF1, regulator of nonsense transcripts 1, nonsense mRNA reducing factor 1, UPF1 regulator of nonsense transcripts homolog (yeast), up-frameshift mutation 1 homolog, yeast Upf1p homolog, nonsense mediated mRNA decay factor

Niveau de qualité

100

Source biologique

goat

Forme d'anticorps

affinity purified immunoglobulin

antibody product type

primary antibodies

Qualité

Powered by Bethyl Laboratories, Inc.

species reactivity

mouse, human

Concentration

1 mg/mL

Application(s)

immunoprecipitation (IP): 2-10 μg/mL
western blot: 1:2,000-1:10000

N° d'accession

NP_002902.2

Expédié(e)(s) dans

wet ice

Temp. de stockage

2-8°C

Gene Information

goat ... UPF1(5976)

Immunogène

The epitope recognized by PLA0010 maps to a region between residue 1075 and the C-terminus (residue 1118) of human Regulator of Nonsense Transcripts 1 (up-frameshift mutation 1 homolog) using the numbering given in entry NP_002902.2 (GeneID 5976).

Forme physique

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Autres remarques

RENT1, also known as UPF1, is a key regulator of the nonsense-mediated mRNA decay (NMD) pathway. The NMD pathway eliminates mRNAs that prematurely terminate during translation and may serve to protect the cells from dominant-negative effects of truncated proteins, or as a means to regulate protein expression. RENT1 is an ATP-dependent 5′- 3′ RNA helicase and ATPase that localizes to the cytoplasm and is part of a post-splicing multiprotein complex as well as an mRNA decay complex.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RID ADR

NONH for all modes of transport

WGK Allemagne

nwg

Flash Point(F)

Not applicable

Point d'éclair C

Not applicable

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