ホームApplications研究・疾患領域薬理学・創薬研究

薬理学・創薬研究

関連資料

Phase I Drug Metabolism
Phase I biotransformation reactions introduce or expose functional groups on the drug with the goal of increasing the polarity of the compound. Although Phase I drug metabolism occurs in most tissues, the primary and first pass site of metabolism occurs during hepatic circulation.
Target Identification & Validation for Early Drug Discovery
Target identification, validation and characterization for early stages of drug discovery. Identifying drug target via genetic association, expression profiling.
Inhibition of Nucleic Acid Synthesis by Antibiotics
Quinolones are a key group of antibiotics that interfere with DNA synthesis by inhibiting topoisomerase, most frequently topoisomerase II (DNA gyrase), an enzyme involved in DNA replication.
3D細胞培養ツールおよび技術
3D細胞培養の概要2D細胞培養と3D細胞培養の比較、3D細胞培養の利点、3D細胞培養技術について紹介します。
腸管排出系トランスポーターと薬物吸収
腸管排出系トランスポーターと薬物吸収に関する論文を報告しました。
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