04476

Hordenine

≥97.0% (HPLC)

• 別名: 2-(4-Hydroxyphenyl)-N,N-dimethylethylamine, 4-(2-Dimethylaminoethyl)phenol, N,N-Dimethyltyramine, p-Hydroxy-N,N-dimethylphenethylamine, Anhaline, Cactine, Eremursin, Peyocactine
• 実験式（ヒル表記法）: C₁₀H₁₅NO
• CAS番号: 539-15-1
• 分子量: 165.23
• NACRES: NA.25
• PubChem Substance ID: 329747931
• UNSPSC Code: 41116107
• EC Number: 208-710-4
• MDL number: MFCD00051462
• Beilstein/REAXYS Number: 2207615

特性

• Quality Segment: 100
• assay: ≥97.0% (HPLC)
• form: powder or crystals
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: CN(C)CCc1ccc(O)cc1
• InChI: 1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3
• InChI key: KUBCEEMXQZUPDQ-UHFFFAOYSA-N

詳細

Application

Hordenine is suitable to study the effect of reed canary grass alkoloids on in vito digestibility. It is also suitable for use as a standard to identify endogenous hordenine in ungerminated and germinated barley by HPLC/diode array detection analysis. Hordenine may be used as an analytical reference material and in research on the activities of phenethylamine type alkaloids.

Biochem/physiol Actions

Hordenine is an alkaloid found in plants, e.g. the roots of germinating barley and marine algae. It is a metabolite in tyrosine metabolism, biosynthesized from tyramine by two subsequent N-methylations, it is metabolized by monoamine oxidase. Hordenine is a sympathomimetic and its pharmacological actions are of interest, as it is occasionally found in post race urine samples. Hordenine inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production. cAMP is involved in the expression of melanogenesis-related proteins. Hordenine may be used in the inhibition of hyperpigmentation. It is present in barley roots from the first day of seed germination, but is not present in seeds.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

安全性情報

• ピクトグラム: GHS07
• 注意喚起語: Warning
• ハザードコード: H315,H319,H335
• 注意事項: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標的臓器: Respiratory system
• 保管分類: 11 - Combustible Solids
• 一体何が起きているの？: WGK 3
• 引火点 (F): Not applicable
• 引火点（°C）: Not applicable