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LO4100

LOPAC®1280-小スケール

別名:

Library of Pharmacologically Active Compounds - small scale

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この商品について

UNSPSC Code:
12352200
EC Number:
200-664-3
NACRES:
NA.77
eCl@ss:
32160702
Form:
liquid
製品LO4100は現在お客様の国では販売されていません。 製品に関するお問い合わせはこちら(テクニカルサービス)
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form

liquid

Quality Segment

drug control

Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

shipped in

dry ice

storage temp.

−20°C

General description

LOPAC® 1280 is an extensively used library of pharmacologically active compounds. This library includes 1,280 marketed drugs, failed development candidates, and small molecules with well-characterized activities. LOPAC 1280 spans a broad molecular weight range, exhibits multiple mechanisms of action and interacts with a variety of biological receptors.
Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (25 μl at 10 mM in DMSO in archival storage racks).

Application

LOPAC® 1280 - Small Scale has been used:
  • in sprouting assay to screen potential lymphangiogenic inhibitors and the signaling pathways involved in lymphangiogenesis
  • for identification of neuroactive compounds by measuring spontaneous activity within single zebrafish embryos by high-content screening assay
  • for high-throughput Screen for ectonucleoside triphosphate diphosphohydrolase-1 (ENTPD1; also known as CD39) and ecto-5′-nucleotidase (CD73) inhibitors

Features and Benefits

Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:

  • Apoptosis
  • G Proteins & Cyclic Nucleotides
  • Gene Regulation & Expression
  • Ion Channels
  • Lipid Signaling
  • Multi-Drug Resistance
  • Neurotransmission
  • Phosphorylation
SDFile provided to construct a database containing:
  • Structure
  • Primary Name
  • Secondary Name
  • Pharmacological Activity
  • Product Number
  • Rack Position

Other Notes

For sale inside of the U.S. only. Customers outside the US should refer to Product Code LO4200.

Legal Information

LOPAC is a registered trademark of Merck KGaA, Darmstadt, Germany


Still not finding the right product?

Explore all of our products under LOPAC®1280-小スケール


ピクトグラム

Skull and crossbonesHealth hazardCorrosionEnvironment

注意喚起語

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 2

保管分類

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

引火点 (F)

188.6 °F

引火点(°C)

87 °C

WGK

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

キットコンポーネントの情報を参照してください

pdsc

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prtr

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fsl

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ishl_indicated

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ishl_notified

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cart

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jan



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試験成績書(COA)

Lot/Batch Number

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質問

1–9/9 質問  
  1. What is the Department of Transportation shipping information for this product?

    1 回答
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      役に立ちましたか?

  2. What is on the LOPAC 1280 - Small Scale Products LO4100 and LO4200 CD?

    1 回答
    1. The CD contains the SDFile - provided to construct a database containing structure, primary name, secondary, Pharmacological Activity. Product number and Rack position.

      役に立ちましたか?

  3. Is the LOPAC 1280 - Small Scale Products LO4100 and LO4200 CD shipped with the product?

    1 回答
    1. Yes, the CD is shipped with the product. If you do not receive it you should contact Sigma-Aldrich Technical Services at techserv@sial.com or 1800-325-5832.

      役に立ちましたか?

  4. Are the LOPAC 1280 - Small Scale Products LO4100 and LO4200 approved for therapeutic use?

    1 回答
    1. Although there are FDA approved drugs in the set, we market them based on their research application and not necessarily their therapeutic indications. All of the information we have is included on the CD that is received with the library. We do not include information from the Physician's Desk Reference.

      役に立ちましたか?

  5. What is the difference between the LOPAC®,1280 product numbers LO4100 and LO1280?

    1 回答
    1. The compound per well in LO4100 is 25 ul at 10mM in DMSO versus 250 ul in the product LO1280

      役に立ちましたか?

  6. Are the LOPAC 1280 - Small Scale Products LO4100 and LO4200  US approved?

    1 回答
    1. About 30% of the collection is made up of drugs approved for use in the US.

      役に立ちましたか?

  7. Where can I find preparation instruction, storage and stability of the LOPAC 1280 - Small Scale Products LO4100 and LO4200?

    1 回答
    1. The information is available in the datasheet of a similar product LO1280.

      役に立ちましたか?

  8. Can I get a list of CAS numbers of the drugs sent with LOPAC 1280 - Small Scale Products LO4100 and LO4200?

    1 回答
    1. There is no CAS number list available.

      役に立ちましたか?

  9. What is the difference between the LOPAC1280 Products LO4100 and LO4200?

    1 回答
    1. These 2 products are the same. LO4100 is the US version versus LO4200 is the International version.

      役に立ちましたか?

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