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Merck

O7885

オカダ酸 カリウム塩 渦鞭毛藻Prorocentrum concavum由来

≥90% (HPLC), powder

別名:

OA

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10 μG

￥14,430

25 μG

￥15,990

50 μG

￥25,060

￥14,430

単価￥22,200割引35%
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この商品について

実験式（ヒル表記法）:
C44H67KO13
CAS番号:
155751-72-7
分子量:
843.09
NACRES:
NA.77
PubChem Substance ID:
24898050
UNSPSC Code:
12352106
MDL number:
MFCD00214356

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製品名

オカダ酸 カリウム塩 渦鞭毛藻Prorocentrum concavum由来, ≥90% (HPLC), powder

InChI

1S/C46H72O13.K/c1-27-20-35(56-46(22-27)36(48)12-15-42(7,59-46)24-43(8,52)40(50)51)28(2)10-14-41(6)17-18-45(58-41)16-11-34-39(57-45)37(49)30(4)38(55-34)33(47)21-29(3)32-23-44(26-54-31(32)5)13-9-19-53-25-44;/h10,14,22,28-29,31-39,47-49,52H,4,9,11-13,15-21,23-26H2,1-3,5-8H3,(H,50,51);/q;+1/p-1/b14-10+;

SMILES string

[K+].CC(CC(O)C1OC2CCC3(CCC(C)(O3)\C=C\C(C)C4CC(C)=CC5(O4)OC(C)(CCC5O)CC(C)(O)C([O-])=O)OC2C(O)C1=C)C6CC7(CCCOC7)COC6C

InChI key

CWKZDWKRECTBCU-KMZJGFRYSA-M

biological source

plant (Prorocentrum concavum)

assay

≥90% (HPLC)

form

powder

color

white

solubility

H2O: 0.1 mg/mL
DMSO: soluble
ethanol: soluble

storage temp.

−20°C

Quality Level

200

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当該品目
O8010O7760O9381
Okadaic acid potassium salt from Prorocentrum concavum ≥90% (HPLC), powder

Sigma-Aldrich

O7885

Okadaic acid potassium salt from Prorocentrum concavum

Okadaic acid ammonium salt from Prorocentrum concavum ≥90% (HPLC), solid

Sigma-Aldrich

O8010

Okadaic acid ammonium salt from Prorocentrum concavum

Okadaic acid sodium salt from Prorocentrum concavum ≥90% (HPLC), film

Sigma-Aldrich

O7760

Okadaic acid sodium salt from Prorocentrum concavum

Okadaic acid from Prorocentrum concavum 92-100% (HPLC)

Sigma-Aldrich

O9381

Okadaic acid from Prorocentrum concavum

form

powder

form

solid

form

film

form

powder

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

92-100% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 0.1 mg/mL, ethanol: soluble, DMSO: soluble

solubility

H2O: 0.1 mg/mL, DMSO: soluble, ethanol: soluble

solubility

0.1% acetic acid in CH3CN: H2O (1:1): 250 μg/mL, clear, colorless

solubility

DMSO: ≥1 mg/mL, ethanol: ≥1 mg/mL, methanol: ≥1 mg/mL, H2O: insoluble

color

white

color

white

color

translucent

color

-

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.
Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
SLCR0004
SLCN4637
SLCK7966
SLCK7962

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Mitchell J George et al.
International journal of molecular sciences, 22(12) (2021-07-03)
Myosin Light Chain (MLC) regulates platelet contraction through its phosphorylation by Myosin Light Chain Kinase (MLCK) or dephosphorylation by Myosin Light Chain Phosphatase (MLCP). The correlation between platelet contraction force and levels of MLC phosphorylation is unknown. We investigate the
Yulan Zhao et al.
Life sciences, 246, 117382-117382 (2020-02-01)
Our preliminary research revealed that metformin, a classic anti-diabetic drug, could rescue Parkin protein expression and mitophagy in high glucose-challenged human renal epithelial cells in vitro, but the molecular mechanism remains to be explored. In the study, Human Renal Cortical
Huijing Yin et al.
Nature communications, 12(1), 4230-4230 (2021-07-11)
Extracellular matrix protein-1 (ECM1) promotes tumorigenesis in multiple organs but the mechanisms associated to ECM1 isoform subtypes have yet to be clarified. We report in this study that the secretory ECM1a isoform induces tumorigenesis through the GPR motif binding to
Yongqiang Chen et al.
Autophagy, 18(6), 1274-1296 (2021-09-18)
Cancer cell growth is dependent upon the sustainability of proliferative signaling and resisting cell death. Macroautophagy/autophagy promotes cancer cell growth by providing nutrients to cells and preventing cell death. This is in contrast to autophagy promoting cell death under some
Chris M Brewer et al.
Developmental cell, 56(19), 2722-2740 (2021-10-06)
Spiny mice (Acomys cahirinus) are terrestrial mammals that evolved unique scar-free regenerative wound-healing properties. Myofibroblasts (MFs) are the major scar-forming cell type in skin. We found that following traumatic injury to ear pinnae, MFs appeared rapidly in both Acomys and
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