O7885

オカダ酸 カリウム塩 渦鞭毛藻Prorocentrum concavum由来

≥90% (HPLC), powder

• 別名: OA
• 実験式（ヒル表記法）: C₄₄H₆₇KO₁₃
• CAS番号: 155751-72-7
• 分子量: 843.09
• NACRES: NA.77
• PubChem Substance ID: 24898050
• UNSPSC Code: 12352106
• MDL number: MFCD00214356
• Assay: ≥90% (HPLC)
• Form: powder

特性

• biological source: plant (Prorocentrum concavum)
• Quality Segment: 200
• assay: ≥90% (HPLC)
• form: powder
• color: white
• solubility: H₂O: 0.1 mg/mL, DMSO: soluble, ethanol: soluble
• storage temp.: −20°C
• SMILES string: [K+].CC(CC(O)C1OC2CCC3(CCC(C)(O3)\C=C\C(C)C4CC(C)=CC5(O4)OC(C)(CCC5O)CC(C)(O)C([O-])=O)OC2C(O)C1=C)C6CC7(CCCOC7)COC6C
• InChI: 1S/C46H72O13.K/c1-27-20-35(56-46(22-27)36(48)12-15-42(7,59-46)24-43(8,52)40(50)51)28(2)10-14-41(6)17-18-45(58-41)16-11-34-39(57-45)37(49)30(4)38(55-34)33(47)21-29(3)32-23-44(26-54-31(32)5)13-9-19-53-25-44;/h10,14,22,28-29,31-39,47-49,52H,4,9,11-13,15-21,23-26H2,1-3,5-8H3,(H,50,51);/q;+1/p-1/b14-10+;
• InChI key: CWKZDWKRECTBCU-KMZJGFRYSA-M

詳細

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

安全性情報

• ピクトグラム: GHS06
• 注意喚起語: Danger
• ハザードコード: H301 + H311 + H331,H315
• 注意事項: P261 - P280 - P301 + P330 + P331 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
• 保管分類: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点 (F): Not applicable
• 引火点（°C）: Not applicable
• PPE（個人用保護具）: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges